Evidence map›Paper›PMID 30988734›Full record

ArticleExperimental and therapeutic medicine2019

miRNA-214 suppresses oxidative stress in diabetic nephropathy via the ROS/Akt/mTOR signaling pathway and uncoupling protein 2.

Shufang Yang, Xiaoqiang Fei, Yu Lu, Bangkui Xu, Yongmei Ma, Hui Wan

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

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  12. Tear Film MicroRNAs as Potential Biomarkers: A Review.International journal of molecular sciences · 2023
    Review
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  14. Article
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  19. Chaperone Sigma1R and Antidepressant Effect.International journal of molecular sciences · 2020
    Review
  20. The Role of microRNAs in Metabolic Syndrome-Related Oxidative Stress.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shufang YangDepartment of Endocrinology, Taizhou People's Hospital, Fifth People's Hospital of Nantong University, Taizhou, Jiangsu 225300, P.R. China.
Xiaoqiang FeiDepartment of Endocrinology, Taizhou People's Hospital, Fifth People's Hospital of Nantong University, Taizhou, Jiangsu 225300, P.R. China.
Yu LuDepartment of Endocrinology, Taizhou People's Hospital, Fifth People's Hospital of Nantong University, Taizhou, Jiangsu 225300, P.R. China.
Bangkui XuDepartment of Endocrinology, Taizhou People's Hospital, Fifth People's Hospital of Nantong University, Taizhou, Jiangsu 225300, P.R. China.
Yongmei MaDepartment of Endocrinology, Taizhou People's Hospital, Fifth People's Hospital of Nantong University, Taizhou, Jiangsu 225300, P.R. China.
Hui WanDepartment of Endocrinology, Wuxi Second People's Hospital, Wuxi, Jiangsu 214000, P.R. China.
Nantong University · CNTaizhou People's Hospital · CNXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, the function of microRNA (miR)-214 on diabetic nephropathy (DN) and diabetes of proximal tubular cells was investigated. Reverse transcription-quantitative polymerase chain reaction was used measure the expression of miR-214 in rats with DN and ELISA was performed to measure oxidative stress and ROS levels. Results indicated that miR-214 expression in the peripheral blood was significantly decreased in rats with DN. The

Indexed as

Aktdiabetic nephropathymammalian target of rapamycinmicroRNA-214reactive oxygen speciesUCP2

Identifiers

PMID30988734
PMCPMC6447795
OpenAlexW2921422368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.