Evidence map›Paper›PMID 30988699›Full record

ReviewBiotechnology for biofuels2019

Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories.

Timothy C Cairns, Xiaomei Zheng, Ping Zheng, Jibin Sun, Vera Meyer

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Extracellular Phosphate Availability ImpactsJournal of fungi (Basel, Switzerland) · 2025
    Article
  11. Review
  12. Pigment Formation byJournal of agricultural and food chemistry · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Towards engineering agaricomycete fungi for terpenoid production.Journal of industrial microbiology & biotechnology · 2024
    Review
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Timothy C Cairns1Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.ORCID 0000-0001-7106-224X
Xiaomei Zheng1Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.ORCID 0000-0001-9136-0666
Ping Zheng1Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Jibin Sun1Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.ORCID 0000-0002-0208-504X
Vera Meyer1Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.ORCID 0000-0002-2298-2258

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Filamentous fungi are harnessed as cell factories for the production of a diverse range of organic acids, proteins, and secondary metabolites. Growth and morphology have critical implications for product titres in both submerged and solid-state fermentations. Recent advances in systems-level understanding of the filamentous lifestyle and development of sophisticated synthetic biological tools for controlled manipulation of fungal genomes now allow rational strain development programs based on data-driven decision making. In this review, we focus on

Indexed as

Aspergillus nigerCell factoryCitric acidFilamentous fungiProtein secretionSecondary metaboliteSynthetic biologySystems biology

Identifiers

PMID30988699
PMCPMC6446404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.