Evidence map›Paper›PMID 30988559›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2019

Outcomes of Intensive Treatment of Adult Acute Myeloid Leukemia Patients: A Retrospective Study From a Single Centre.

Jayachandran Perumal Kalaiyarasi, Prasanth Ganesan, Krishnarathinam Kannan, Trivadi S Ganesan, Venkatraman Radhakrishnan, Manikandan Dhanushkodi, S Krupashankar, Nikita Mehra, Tenali Gnana Sagar

Abstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. AML With HIV Infection in The Era of Precision Oncology - Do We See The Light At The End of The Tunnel?Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  3. Observational
  4. Article
  5. Outcomes of HIDAC 18 g Versus IDAC 9 g in Consolidation Therapy of Acute Myeloid Leukemia: A Retrospective Study.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2022
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jayachandran Perumal KalaiyarasiDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.
Prasanth GanesanDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.ORCID 0000-0003-2762-6591
Krishnarathinam KannanDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.
Trivadi S GanesanDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.
Venkatraman RadhakrishnanDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.
Manikandan DhanushkodiDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.
S KrupashankarDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.
Nikita MehraDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.
Tenali Gnana SagarDepartment of Medical Oncology, Cancer Institute (WIA), 36, Sardar Patel Road, Guindy, Chennai, Tamilnadu India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute Myeloid Leukemia (AML) is a very aggressive cancer with difficult treatment and poor outcomes. The treatment of these patients is quite challenging due to various reasons including the need for extensive supportive care, and high cost of therapy. Reports on outcomes from India are few.

methodsWe analyzed 93 adult patients (≥ 18 years) with AML who were treated with curative intent between 2007 and 2014. Patients received daunorubicin at dose of 60-90 mg/m

resultsThe median age was 37 (18-66) years; males: 52%. Conventional cytogenetics (N = 63) showed 23% (N = 15), 56% (N = 35), 27% (N = 13) in good, intermediate risk and poor risk category respectively.

conclusionsOutcomes in adult AML are generally poor. Many patients with high risk disease don't receive allogenic transplantation in CR1. Increased availability of allogenic stem cell transplantation may help to improve outcomes.

Indexed as

Acute myeloid leukemiaDaunorubicinIndiaMortalityOutcomesRisk stratification

Identifiers

PMID30988559
PMCPMC6439037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.