ReviewNature human behaviour2019
Process-based framework for precise neuromodulation.
Review in Nature human behaviour, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03964545 (Proof-of-concept and Validity of Amygdala-neurofeedback in Adolescent Patients With Emotion Dysregulation), which is not on this map. Cited by 45 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Proof-of-concept and Validity of Amygdala-neurofeedback in Adolescent Patients With Emotion Dysregulation
Who cites it
45 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Music in the loop: a systematic review of current neurofeedback methodologies using music.Frontiers in neuroscience · 2025Pooled it
- Review of EEG-based neurofeedback as a therapeutic intervention to treat depression.Psychiatry research. Neuroimaging · 2023Pooled it
- The Potential of Functional Near-Infrared Spectroscopy-Based Neurofeedback-A Systematic Review and Recommendations for Best Practice.Frontiers in neuroscience · 2020Pooled it
- Upregulation of reward mesolimbic activity and immune response to vaccination: a randomized controlled trial.Nature medicine · 2026Trial
- An intelligent sport training method based on EEG neurofeedback.Scientific reports · 2025Trial
- Targeted limbic self-neuromodulation for alleviating central sensitization symptoms in fibromyalgia.BMC medicine · 2025Trial
- Amygdala-related electroencephalogram neurofeedback as add-on therapy for treatment-resistant childhood sexual abuse posttraumatic stress disorder: feasibility study.Psychiatry and clinical neurosciences · 2024Trial
- Alpha activity neuromodulation induced by individual alpha-based neurofeedback learning in ecological context: a double-blind randomized study.Scientific reports · 2021Trial
- An fMRI-informed EEG model of the amygdala is associated with salience network dynamics during naturalistic emotional stimulation.Molecular psychiatry · 2026Article
- Real-Time EEG-Derived Amygdala Neurofeedback for Post-Traumatic Stress Disorder: A Clinical Case Series.Journal of clinical medicine · 2026Article
- A novel music-based real-time fMRI neurofeedback interface modulates interhemispheric connectivity and enhances mood.Frontiers in psychiatry · 2026Article
- Reward System EEG-fMRI-Pattern Neurofeedback for Major Depressive Disorder with Anhedonia: A Multicenter Pilot Study.Brain sciences · 2025Article
- Amygdala EFP Neurofeedback Effects on PTSD Symptom Clusters and Emotional Regulation Processes.Journal of clinical medicine · 2025Article
- Neurofeedback Training Facilitates Awareness and Enhances Emotional Well-being Associated with Real-World Meditation Practice: A 7-T MRI Study.Mindfulness · 2025Article
- Aesthetics, illusion of success and age interactions: disentangling effects in the closed-loop design with sham neurofeedback training.Frontiers in human neuroscience · 2025Article
- Neuromodulation Strategies in Lifelong Bipolar Disorder: A Narrative Review.Behavioral sciences (Basel, Switzerland) · 2024Review
- Amygdala self-neuromodulation capacity as a window for process-related network recruitment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Individualized functional magnetic resonance imaging neuromodulation enhances visuospatial perception: a proof-of-concept study.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- From lab to life: challenges and perspectives of fNIRS for haemodynamic-based neurofeedback in real-world environments.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional MRI neurofeedback (NF) allows humans to self-modulate neural patterns in specific brain areas. This technique is regarded as a promising tool to translate neuroscientific knowledge into brain-guided psychiatric interventions. However, its clinical implementation is restricted by unstandardized methodological practices, by clinical definitions that are poorly grounded in neurobiology, and by lack of a unifying framework that dictates experimental choices. Here we put forward a new framework, termed 'process-based NF', which endorses a process-oriented characterization of mental dysfunctions to form precise and effective psychiatric treatments. This framework relies on targeting specific dysfunctional mental processes by modifying their underlying neural mechanisms and on applying process-specific contextual feedback interfaces. Finally, process-based NF offers designs and a control condition that address the methodological shortcomings of current approaches, thus paving the way for a precise and personalized neuromodulation.
Indexed as
Identifiers
30988481What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.