Evidence map›Paper›PMID 30988456›Full record

ArticleScientific reports2019

Metabolomic profiles differ among unique genotypes of a threatened Caribbean coral.

Kathryn E Lohr, Ram B Khattri, Joy Guingab-Cagmat, Emma F Camp, Matthew E Merritt, Timothy J Garrett, Joshua T Patterson

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. PeerJ · 2023
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  18. Isolated murine skeletal muscles utilize pyruvate over glucose for oxidation.Metabolomics : Official journal of the Metabolomic Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathryn E LohrProgram in Fisheries and Aquatic Sciences, School of Forest Resources and Conservation, University of Florida/IFAS, Gainesville, FL, USA. kelohr@ufl.edu.ORCID http://orcid.org/0000-0002-3580-3431
Ram B KhattriDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Joy Guingab-CagmatDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
Emma F CampClimate Change Cluster, University of Technology Sydney, Ultimo, NSW, Australia.ORCID http://orcid.org/0000-0003-1962-1336
Matthew E MerrittDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Timothy J GarrettDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
Joshua T PattersonProgram in Fisheries and Aquatic Sciences, School of Forest Resources and Conservation, University of Florida/IFAS, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-0941-2154

Funding

Southeast Resource Center for Integrated Metabolomics (SECIM)U24DK097209 · NIDDK · UNIVERSITY OF FLORIDA · PI EDISON, ARTHUR S, YOST, RICHARD A. · 2013 to 2017
$9.2M
NIDDK NIH HHS U24 DK097209
6 · The paper itself

Abstract

Global threats to reefs require urgent efforts to resolve coral attributes that affect survival in a changing environment. Genetically different individuals of the same coral species are known to exhibit different responses to the same environmental conditions. New information on coral physiology, particularly as it relates to genotype, could aid in unraveling mechanisms that facilitate coral survival in the face of stressors. Metabolomic profiling detects a large subset of metabolites in an organism, and, when linked to metabolic pathways, can provide a snapshot of an organism's physiological state. Identifying metabolites associated with desirable, genotype-specific traits could improve coral selection for restoration and other interventions. A key step toward this goal is determining whether intraspecific variation in coral metabolite profiles can be detected for species of interest, however little information exists to illustrate such differences. To address this gap, we applied untargeted

Indexed as

Endangered SpeciesAnimalsAnthozoaCaribbean RegionChromatography, High Pressure LiquidCoral ReefsGenotypeGenotyping TechniquesMass SpectrometryMetabolomeMetabolomicsPhenotypeProton Magnetic Resonance Spectroscopy

Identifiers

PMID30988456
PMCPMC6465396

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.