ArticleScientific reports2019
Stage-specific transcriptome of Bursaphelenchus xylophilus reveals temporal regulation of effector genes and roles of the dauer-like stages in the lifecycle.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
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- The New Nematicide Cyclobutrifluram Targets the Mitochondrial Succinate Dehydrogenase Complex inInternational journal of molecular sciences · 2024Article
- Differences of Pine Wood Nematode (Biology · 2024Article
- Pine wilt disease: what do we know from proteomics?BMC plant biology · 2024Review
- Functional Characterization of ShK Domain-Containing Protein in the Plant-Parasitic NematodePlants (Basel, Switzerland) · 2024Article
- AdvancingPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Possible stochastic sex determination in Bursaphelenchus nematodes.Nature communications · 2022Article
- The key molecular pattern BxCDP1 ofFrontiers in plant science · 2022Article
- On the role of dauer in the adaptation of nematodes to a parasitic lifestyle.Parasites & vectors · 2021Review
- Transcriptome Analysis and miRNA Target Profiling at Various Stages of Root-Knot NematodeInternational journal of molecular sciences · 2021Article
- Genome Expression Dynamics Reveal the Parasitism Regulatory Landscape of the Root-Knot NematodeGenes · 2021Article
- Molecular variation among virulent and avirulent strains of the quarantine nematode Bursaphelenchus xylophilus.Molecular genetics and genomics : MGG · 2021Article
- Genetic characteristics of Bursaphelenchus xylophilus third-stage dispersal juveniles.Scientific reports · 2021Article
- Comparative Analysis ofFrontiers in plant science · 2021Article
- Improving Transgenesis Efficiency and CRISPR-Associated Tools Through Codon Optimization and Native Intron Addition inGenetics · 2020Article
- Speciation and adaptive evolution reshape antioxidant enzymatic system diversity across the phylum Nematoda.BMC biology · 2020Article
- Nearly Complete Genome Assembly of the Pinewood Nematode Bursaphelenchus xylophilus Strain Ka4C1.Microbiology resource announcements · 2020Article
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pine wood nematode Bursaphelenchus xylophilus is the causal agent of pine wilt disease, one of the most devastating forest diseases in East Asian and West European countries. The lifecycle of B. xylophilus includes four propagative larval stages and gonochoristic adults which are involved in the pathogenicity, and two stages of dispersal larvae involved in the spread of the disease. To elucidate the ecological roles of each developmental stage in the pathogenic life cycle, we performed a comprehensive transcriptome analysis using RNA-seq generated from all developmental stages of B. xylophilus and compared transcriptomes between stages. We found more than 9000 genes are differentially expressed in at least one stage of the life cycle including genes involved in general nematode biology such as reproduction and moulting but also effector genes likely to be involved in parasitism. The dispersal-stage transcriptome revealed its analogy to C. elegans dauer and the distinct roles of the two larval stages from each other regarding survival and transmission. This study provides important insights and resources to understand B. xylophilus parasitic biology.
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