Evidence map›Paper›PMID 30988331›Full record

ArticleScientific reports2019

Effects of a phytogenic, alone and associated with potassium diformate, on tilapia growth, immunity, gut microbiome and resistance against francisellosis.

S A Suphoronski, R T Chideroli, C T Facimoto, R M Mainardi, F P Souza, N M Lopera-Barrero, G F A Jesus, M L Martins, G W Di Santis, A de Oliveira and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Feed Additive Potassium Diformate PreventsAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Article
  9. The Effect of a Total Fishmeal Replacement byLife (Basel, Switzerland) · 2021
    Article
  10. Article
  11. Effect ofFrontiers in microbiology · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

S A SuphoronskiLaboratory of Fish Bacteriology (LABBEP) - Department of Preventing Veterinary Medicine, State University of Londrina, Londrina, PR, Brazil.
R T ChideroliLaboratory of Fish Bacteriology (LABBEP) - Department of Preventing Veterinary Medicine, State University of Londrina, Londrina, PR, Brazil.
C T FacimotoLaboratory of Fish Bacteriology (LABBEP) - Department of Preventing Veterinary Medicine, State University of Londrina, Londrina, PR, Brazil.
R M MainardiLaboratory of Fish Bacteriology (LABBEP) - Department of Preventing Veterinary Medicine, State University of Londrina, Londrina, PR, Brazil.
F P SouzaDepartment of Animal Science, State University of Londrina, Londrina, PR, Brazil.
N M Lopera-BarreroDepartment of Animal Science, State University of Londrina, Londrina, PR, Brazil.
G F A JesusNucleus of studies in Aquaculture Pathology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
M L MartinsNucleus of studies in Aquaculture Pathology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
G W Di SantisLaboratory of Fish Bacteriology (LABBEP) - Department of Preventing Veterinary Medicine, State University of Londrina, Londrina, PR, Brazil.
A de OliveiraLaboratory of Microbial Biotechnology (LABIM) and Laboratory of Electron Microscopy and Microanalysis, State University of Londrina, Londrina, PR, Brazil.ORCID http://orcid.org/0000-0003-1556-5146
G S GonçalvesFishing Institute (APTA-SP), São José do Rio Preto, SP, Brazil.
R DariMiXscience, Bruz, Brittany, France.
S FrouelMiXscience, Bruz, Brittany, France.
U P PereiraLaboratory of Fish Bacteriology (LABBEP) - Department of Preventing Veterinary Medicine, State University of Londrina, Londrina, PR, Brazil. upaduapereira@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work evaluated the effects of dietary supplementation of A-Live (phytogenic) either individually or in combination with Aquaform (potassium diformate, acidifier) on juvenile Nile tilapia (Oreochromis niloticus) growth performance, innate immune parameters, gut microbiome, and resistance against Francisella noatunensis subsp. orientalis challenge. Each experimental group contained 140 fishes (34.3 ± 0.33) in two 150L tanks. The experimental design consisted of five groups: a negative control; treated groups (G1, G2, G3) supplemented with different concentrations of A-Live and Aquaform in the feed; and a positive control (PC) for pathogen infection. Groups G1, G2, G3, and PC were challenged with Francisella spp. after 15 days. After infection, the mortality was significantly lower in groups G1, G2, and G3 (p < 0.01). Furthermore, these groups showed significant increase (p < 0.05) in daily weight gain, feed conversion rate, and specific growth rate. The PC group presented increase (p < 0.05) in the leukocytes and neutrophils number. Innate immunity parameters showed no difference between treatments after infection. Microbiome analysis revealed an increased number of bacteria belonging to the Vibrionaceae family after pathogen infection suggesting a secondary pathogen function of these bacteria. These results validate the beneficial effects of these products in tilapia farming.

Indexed as

Animal FeedAnimalsAquacultureCichlidsDietary SupplementsDisease ResistanceFish DiseasesFormatesFrancisellaGastrointestinal MicrobiomeImmunity, InnateMicrobial Sensitivity TestsPlant ExtractsFormatesformic acidPlant Extracts

Identifiers

PMID30988331
PMCPMC6465292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.