ArticleScientific reports2019
Transcriptome Analyses of Heart and Liver Reveal Novel Pathways for Regulating Songbird Migration.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Massive Genomic and Transcriptomic Changes Within a Young Inversion Polymorphism in the Absence of Degeneration.Molecular ecology · 2026Article
- To Migrate or not to Migrate? Exploring the Genomic Basis of Partial Migratory Behavior in Bats.Genome biology and evolution · 2025Article
- Brain gene expression reveals pathways underlying nocturnal migratory restlessness.Scientific reports · 2024Article
- Inter-organ differences in redox imbalance and apoptosis depict metabolic resilience in migratory redheaded buntings.Scientific reports · 2024Article
- Avian migration clocks in a changing world.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Review
- Long noncoding RNAs and mRNAs profiling in ovary during laying and broodiness in Taihe Black-Bone Silky Fowls (Gallus gallus Domesticus Brisson).BMC genomics · 2024Article
- Adaptive Regulation of Stopover Refueling during Bird Migration: Insights from Whole Blood Transcriptomics.Genome biology and evolution · 2023Article
- Dynamic molecular evolution of a supergene with suppressed recombination in white-throated sparrows.eLife · 2022Article
- Migratory disposition alters lean mass dynamics and protein metabolism in migratory white-throated sparrows (American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Age-dependent timing and routes demonstrate developmental plasticity in a long-distance migratory bird.The Journal of animal ecology · 2022Article
- Transcriptomic Diversity in the Livers of South African Sardines Participating in the Annual Sardine Run.Genes · 2021Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many birds undertake long biannual voyages during the night. During these times of the year birds drastically reduce their amount of sleep, yet curiously perform as well on tests of physical and cognitive performance than during non-migrating times of the year. This inherent physiological protection disappears when birds are forced to stay awake at other times of the year; thus these protective changes are only associated with the nocturnal migratory state. The goal of the current study was to identify the physiological mechanisms that confer protection against the consequences of sleep loss while simultaneously allowing for the increased physical performance required for migration. We performed RNA-seq analyses of heart and liver collected from birds at different times of day under different migratory states and analyzed these data using differential expression, pathway analysis and WGCNA. We identified changes in gene expression networks implicating multiple systems and pathways. These pathways regulate many aspects of metabolism, immune function, wound repair, and protection of multiple organ systems. Consequently, the circannual program controlling the appearance of the migratory phenotype involves the complex regulation of diverse gene networks associated with the physical demands of migration.
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