ArticleBioscience reports2019
CircLMTK2 acts as a novel tumor suppressor in gastric cancer.
Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The prognostic value of circRNAs for gastric cancer: A systematic review and meta-analysis.Cancer medicine · 2020Pooled it
- Advanced approaches of the use of circRNAs as a replacement for cancer therapy.Non-coding RNA research · 2024Review
- Cancer-related circular RNA: diverse biological functions.Cancer cell international · 2021Review
- Differential Gene Expression Analysis Reveals Global LMTK2 Regulatory Network and Its Role in TGF-β1 Signaling.Frontiers in oncology · 2021Article
- LMTK2 as Potential Biomarker for Stratification between Clinically Insignificant and Clinically Significant Prostate Cancer.Journal of oncology · 2021Article
- The function and mechanism of circular RNAs in gastrointestinal tumours.Cell proliferation · 2020Review
- Circular RNA is a popular molecule in tumors of the digestive system (Review).International journal of oncology · 2020Review
- Comprehensive RNA Sequencing in Adenoma-Cancer Transition Identified Predictive Biomarkers and Therapeutic Targets of Human CRC.Molecular therapy. Nucleic acids · 2020Article
- Circular RNA circMAN2B2 promotes growth and migration of gastric cancer cells by down-regulation of miR-145.Journal of clinical laboratory analysis · 2020Article
- Circular RNAs in Gastric Cancer: Potential Biomarkers and Therapeutic Targets.BioMed research international · 2020Review
- Circ_0032821 acts as an oncogene in cell proliferation, metastasis and autophagy in human gastric cancer cells in vitro and in vivo through activating MEK1/ERK1/2 signaling pathway.Cancer cell international · 2020Article
- Circ_0001023 Promotes Proliferation and Metastasis of Gastric Cancer Cells Through miR-409-3p/PHF10 Axis.OncoTargets and therapy · 2020Article
- circ-FNTA accelerates proliferation and invasion of bladder cancer.Oncology letters · 2020Article
- circLMTK2 acts as a sponge of miR-150-5p and promotes proliferation and metastasis in gastric cancer.Molecular cancer · 2019Article
- A circular RNA fromAging · 2019Article
- Current Understanding of Circular RNAs in Gastric Cancer.Cancer management and research · 2019Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, circRNAs have been found to play regulatory roles in cancer. In the present study, we aimed to investigate the characteristics and effect of circLMTK2, and its potential role as a novel biomarker in cases of gastric cancer (GC). About 111 pairs of clinical tissues from patients were collected for circLMTK2 expression investigation. Afterward, the relationship of circLMTK2 expression level and clinical features, such as survival, tumor size and so on, were analyzed, along with a multivariate Cox hazards analysis. Finally, malignant biological properties, like cell viability and mobility, were explored in cell line MGC-803. We found that circLMTK2 was a stable circRNA generated from the back-spliced Exon 10 and Exon 11 of the LMTK2 gene in GC cells. CircLMTK2 expression was significantly down-regulated in gastric carcinoma tissue specimens (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.