Evidence map›Paper›PMID 30988059›Full record

ArticleInfection and immunity2019

The Autotransporter IcsA Promotes Shigella flexneri Biofilm Formation in the Presence of Bile Salts.

Volkan K Köseoğlu, Chelsea P Hall, Eric M Rodríguez-López, Hervé Agaisse

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Microbial genomics · 2025
    Article
  9. A RecombinantInternational journal of molecular sciences · 2024
    Article
  10. Epithelial Cell Infection Analyses with Shigella.Journal of visualized experiments : JoVE · 2024
    Article
  11. Review
  12. Article
  13. Bacterial biofilms in the human body: prevalence and impacts on health and disease.Frontiers in cellular and infection microbiology · 2023
    Review
  14. Article
  15. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Shigella Outer Membrane Vesicles as Promising Targets for Vaccination.International journal of molecular sciences · 2022
    Review
  18. Review
  19. Article
  20. Wolf in Sheep's Clothing:Microorganisms · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Volkan K KöseoğluDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Chelsea P HallDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Eric M Rodríguez-LópezDepartment of Biology, University of Puerto Rico at Ponce, Ponce, Puerto Rico, USA.
Hervé AgaisseDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA hfa5y@virginia.edu.
University of Virginia · USUniversity of Puerto Rico at Ponce · PR

Funding

UNIVERSITY OF PUERTO RICO PONCE RESEARCH INITIATIVE FOR SCIENTIFIC ENHANCEMENT: UR25GM096955 · NIGMS · UNIVERSITY OF PUERTO RICO PONCE · PI SUAREZ-MARTINEZ, EDU B · 2011 to 2020
$5.7M
Mechanisms of intracellular pathogen disseminationR01AI073904 · NIAID · YALE UNIVERSITY · PI AGAISSE, HERVE F · 2007 to 2022
$5.5M
Global Biothreats Training ProgramT32AI055432 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CRISS, ALISON K, PETRI, WILLIAM A · 2003 to 2022
$4.0M
NIAID NIH HHS R01 AI073904NIAID NIH HHS T32 AI055432NIGMS NIH HHS R25 GM096955
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial Outer Membrane ProteinsBacterial ProteinsBile Acids and SaltsBiofilmsDNA-Binding ProteinsShigella flexneriTranscription FactorsType V Secretion SystemsBacterial Outer Membrane ProteinsBacterial ProteinsBile Acids and SaltsDNA-Binding ProteinsTranscription FactorsType V Secretion SystemsvirG protein, Shigella flexneriactinautotransporterbilebiofilmcholic aciddeoxycholicdisseminationIcsAShigella flexneri

Identifiers

PMID30988059
PMCPMC6589070
OpenAlexW2939240751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.