Evidence map›Paper›PMID 30988054›Full record

ArticleInfection and immunity2019

Functional Antibodies against Placental Malaria Parasites Are Variant Dependent and Differ by Geographic Region.

Justin Doritchamou, Andrew Teo, Robert Morrison, Gunjan Arora, Jennifer Kwan, Javier Manzella-Lapeira, Sarimar Medina-Maldonado, Jean Langhorne, Lars Hviid, David L Narum and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. VAR2CSA-Mediated Host Defense Evasion ofFrontiers in immunology · 2020
    Review
  11. Placental Malaria.Current tropical medicine reports · 2020
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Justin DoritchamouLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.ORCID 0000-0002-4589-7216
Andrew TeoLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Robert MorrisonLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Gunjan AroraLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Jennifer KwanLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Javier Manzella-LapeiraLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Sarimar Medina-MaldonadoEM Unit/RTB Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
Jean LanghorneLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Lars HviidCentre for Medical Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1698-4927
David L NarumLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Alassane DickoMalaria Research and Training Center, Faculty of Medicine, Pharmacy and Dentistry, University of Sciences Techniques and Technologies of Bamako, Bamako, Mali.
Michal FriedLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Patrick E DuffyLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA patrick.duffy@nih.gov.
National Institute of Allergy and Infectious Diseases · USThe Francis Crick Institute · GBUniversity of Copenhagen · DK

Funding

Malaria Pathogenesis in young children and vaccine discoveryZIAAI001134 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DUFFY, PATRICK · 2010 to 2025
$11.3M
Malaria Pathogenesis in Pregnant Women and Young ChildrenZIAAI001153 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FRIED, MICHAL · 2011 to 2025
$9.5M
Pregnancy Malaria Vaccine developmentZIAAI001176 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DUFFY, PATRICK · 2012 to 2025
$5.6M
Cancer Research UK FC001101Medical Research Council FC10101Wellcome Trust
6 · The paper itself

Abstract

During pregnancy,

Indexed as

Antibodies, ProtozoanAntigens, ProtozoanErythrocytesFemaleHumansMalaria, FalciparumPlacentaPlasmodium falciparumPregnancyAntibodies, ProtozoanAntigens, Protozoanantibodybinding inhibitionmalariaopsonizing phagocytosisPlasmodium falciparumpregnancy

Identifiers

PMID30988054
PMCPMC6589062
OpenAlexW2940027195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.