ArticleThe oncologist2019
Addressing the Financial Burden of Cancer Clinical Trial Participation: Longitudinal Effects of an Equity Intervention.
Article in The oncologist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- A Review of Medical Mistrust Across the Cancer Continuum of Care and Current Interventions.Journal of community health · 2025Pooled it
- Impact of sociodemographic determinants on enrollment into contemporary lymphoma clinical trials: a systematic review.The oncologist · 2025Pooled it
- Interventions to mitigate cancer-related medical financial hardship: A systematic review and meta-analysis.Cancer · 2024Pooled it
- Effects of socioeconomic status on enrollment in clinical trials for cancer: A systematic review.Cancer medicine · 2024Pooled it
- Representation and Outcomes of Older Adults in Practice-Changing Oncology Trials in the Era of Novel Therapies: A Guideline Appraisal.Journal of the National Comprehensive Cancer Network : JNCCN · 2022Pooled it
- Financial reimbursement for clinical trial participation costs: a pilot feasibility study.JNCI cancer spectrum · 2026Trial
- Financial Toxicity in a Phase I/II Trial of LV20.19 CAR-T Cell for B-cell Malignancies: A Longitudinal, Qualitative Study.Transplantation and cellular therapy · 2026Trial
- A point-of-care pilot randomized intervention to connect patients with cancer-induced financial toxicity to telehealth financial counseling.Cancer causes & control : CCC · 2024Trial
- Assessment of Financial Toxicity Among Older Adults With Advanced Cancer.JAMA network open · 2020Trial
- The LIFT UP study: feasibility of systematically identifying and addressing resource needs in those with metastatic breast cancer.Breast cancer research and treatment · 2026Article
- Use of supportive care services and advance care planning among early phase oncology clinical trial participants.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Design of a cluster randomized multi-level intervention to decrease barriers to minority cancer patient referral and enrollment to cancer clinical trials: The ACT WONDERContemporary clinical trials · 2025Article
- Barriers and facilitators to representative acute leukemia trial participation at National Cancer Institute-designated comprehensive cancer centers.The oncologist · 2025Article
- Financial Toxicity in Cancer Clinical Trials: An Issue in Need of Clarity and Solutions.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025Article
- A Formative Evaluation of Interventions to Enhance Clinical Trial Diversity Guided by the Socioecological Model.Cancers · 2025Article
- Social Needs in Cancer Survivors: A Scoping Review and Future Directions.Current oncology reports · 2025Article
- Financial Toxicity Among Patients With Advanced Solid Tumors Participating in Early-Phase Clinical Trials.JCO oncology practice · 2025Article
- The Importance of Including Underserved Populations in Research.Pharmaceutical medicine · 2025Review
- Cancer clinical trial participation: a qualitative study of Black/African American communities' and patient/survivors' recommendations.JNCI cancer spectrum · 2025Article
- Interventions to Address Cancer-Related Financial Hardship: A Scoping Review and Call to Action.JCO oncology practice · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundThe financial burden experienced by patients with cancer represents a barrier to clinical trial participation, and interventions targeting patients' financial concerns are needed. We sought to assess the impact of an equity intervention on clinical trial patients' financial burden. MATERIALS AND
methodsWe developed an equity intervention to reimburse nonclinical expenses related to trials (e.g., travel and lodging). From July 2015 to July 2017, we surveyed intervention and comparison patients matched by age, sex, cancer type, specific trial, and trial phase. We longitudinally assessed financial burden (e.g., trial-related travel and lodging cost concerns, financial wellbeing [FWB] with the COmprehensive Score for financial Toxicity [COST] measure) at baseline, day 45, and day 90. We used longitudinal models to assess intervention effects over time.
resultsAmong 260 participants, intervention patients were more likely than comparison patients to have incomes under $60,000 (52% vs. 24%,
conclusionCancer clinical trial participants may experience substantial financial issues, and this equity intervention demonstrates encouraging results for addressing these patients' longitudinal financial burden. IMPLICATIONS FOR PRACTICE: Clinical trials are critical for developing novel therapies for patients with cancer, yet financial barriers may discourage some patients from participating in cancer clinical trials. This study found that patients who received financial assistance from an equity intervention experienced significant improvements over time in their concerns about the cost of travel and lodging associated with clinical trials compared with comparison patients who did not receive financial assistance from the equity intervention. Among cancer clinical trial participants, an equity intervention shows potential for addressing patients' concerns regarding clinical trial-related travel and lodging expenses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.