Evidence map›Paper›PMID 30988006›Full record

ArticleThe Journal of biological chemistry2019

Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates.

Andrew A Butler, Jinsong Zhang, Candice A Price, Joseph R Stevens, James L Graham, Kimber L Stanhope, Sarah King, Ronald M Krauss, Andrew A Bremer, Peter J Havel

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
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  15. Serum adropin level in wet-type age-related macular degeneration.International journal of retina and vitreous · 2024
    Article
  16. Article
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  18. Serum Adropin Levels Are Elevated in Patients With Hyperthyroidism.International journal of endocrinology · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Andrew A ButlerFrom the Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri 63104, andrew.butler@health.slu.edu.ORCID 0000-0001-7196-0170
Jinsong ZhangFrom the Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri 63104.
Candice A Pricethe Department of Molecular Biosciences, School of Veterinary Medicine and Department of Nutrition, University of California, Davis, Davis, California 95616.
Joseph R StevensFrom the Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri 63104.
James L Grahamthe Department of Molecular Biosciences, School of Veterinary Medicine and Department of Nutrition, University of California, Davis, Davis, California 95616.ORCID 0000-0001-6507-8149
Kimber L Stanhopethe Department of Molecular Biosciences, School of Veterinary Medicine and Department of Nutrition, University of California, Davis, Davis, California 95616.ORCID 0000-0002-2474-0914
Sarah Kingthe Children's Hospital Oakland Research Institute, Oakland, California 94609, and.
Ronald M Kraussthe Children's Hospital Oakland Research Institute, Oakland, California 94609, and.
Andrew A Bremerthe Department of Pediatrics, Vanderbilt University, Nashville, Tennessee 37232.
Peter J Havelthe Department of Molecular Biosciences, School of Veterinary Medicine and Department of Nutrition, University of California, Davis, Davis, California 95616, pjhavel@ucdavis.edu.
University of California, Davis · USSaint Louis University · USChildren’s Institute · USVanderbilt University · US

Funding

UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU2CDK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2016 to 2021
$5.9M
Adverse Metabolic Effects of Dietary Sugar _ Ad Libitum vs Energy-Balanced DietsR01HL121324 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HAVEL, PETER J, SCHWARZ, JEAN-MARC · 2014 to 2019
$4.2M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU24DK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2015
$4.1M
Effects of fish oil and alpha lipoic on the progression of insulin resistanceR21AT003645 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HAVEL, PETER J · 2006 to 2008
$591k
Role of adropin in maintaining cognitive functionR21NS108138 · NINDS · SAINT LOUIS UNIVERSITY · PI BUTLER, ANDREW ALISTAIR · 2018 to 2019
$417k
NCCIH NIH HHS R21 AT003645NCRR NIH HHS UL1 RR024146NHLBI NIH HHS R01 HL121324NICHD NIH HHS K12 HD051958NIDDK NIH HHS U24 DK092993NIDDK NIH HHS U2C DK092993NINDS NIH HHS R21 NS108138
6 · The paper itself

Abstract

Mouse studies linking adropin, a peptide hormone encoded by the energy homeostasis-associated (

Indexed as

Weight GainAnimalsAtherosclerosisBiomarkersDietDyslipidemiasFructoseGlucoseIntercellular Signaling Peptides and ProteinsMacaca mulattaMaleMice, TransgenicObesityPapioBiomarkersEnho protein, mouseFructoseGlucoseIntercellular Signaling Peptides and Proteinsapolipoproteincircadiandyslipidemiaepigeneticsglucose metabolisminsulin resistanceleptinnutritionobesitytype 2 diabetes

Identifiers

PMID30988006
PMCPMC6597842
OpenAlexW2939733089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.