Evidence map›Paper›PMID 30987993›Full record

ArticleBMJ open2019

Opportunities and challenges of a novel cardiac output response to stress (CORS) test to enhance diagnosis of heart failure in primary care: qualitative study.

Sarah Charman, Nduka Okwose, Gregory Maniatopoulos, Sara Graziadio, Tamara Metzler, Helen Banks, Luke Vale, Guy A MacGowan, Petar M Seferović, Ahmet Fuat and 4 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06377319 (Clinical Validation of an Artificial Intelligence Based Decision Support System for Predicting Risk, Diagnosis, and Progression of Heart Failure), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06377319 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Validation of an Artificial Intelligence Based Decision Support System for Predicting Risk, Diagnosis, and Progression of Heart Failure

TypeobservationalSponsorCoventry UniversityRan2024 to 2027Enrolled1,600ConditionsHeart FailureArmsCardiac Output Response to Stress (CORS) test
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sarah CharmanCardiovascular Research Centre, Newcastle University, Newcastle, UK.
Nduka OkwoseCardiovascular Research Centre, Newcastle University, Newcastle, UK.
Gregory ManiatopoulosInstitute of Health and Society, Newcastle University, Newcastle, UK.
Sara GraziadioNIHR In Vitro Diagnostics Co-operative, Newcastle University, Newcastle, UK.
Tamara MetzlerCardiovascular Research Centre, Newcastle University, Newcastle, UK.
Helen BanksCardiovascular Research Centre, Newcastle University, Newcastle, UK.
Luke ValeHealth Economics Group, Institute of Health and Society, Newcastle University, Newcastle, UK.
Guy A MacGowanInstitute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-2685-4165
Petar M SeferovićCardiology, University of Belgrade School of Medicine, Belgrade, Serbia.
Ahmet FuatPrimary Care, Carmel Medical Practice, Darlington, UK.
Christi DeatonCambridge Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Jonathan MantGeneral Practice and Primary Care Research Unit, University of Cambridge, Cambridge, UK.
Richard F D HobbsDepartment of Primary Health Care, University of Oxford, Oxford, UK.
Djordje G JakovljevicInstitute for Ageing and Health, Newcastle University, Newcastle, UK.

Funding

Medical Research Council BH161161Medical Research Council MC_PC_15030Medical Research Council MR/K02325X/1
6 · The paper itself

Abstract

objectiveTo explore the role of the novel cardiac output response to stress (CORS), test in the current diagnostic pathway for heart failure and the opportunities and challenges to potential implementation in primary care.

designQualitative study using semistructured in-depth interviews which were audio recorded and transcribed verbatim. Data from the interviews were analysed thematically using an inductive approach.

settingNewcastle upon Tyne, UK.

participantsFourteen healthcare professionals (six males, eight females) from primary (general practitioners (GPs), nurses, healthcare assistant, practice managers) and secondary care (consultant cardiologists).

resultsFour themes relating to opportunities and challenges surrounding the implementation of the new diagnostic technology were identified. These reflected that the adoption of CORS test would be an advantage to primary care but the test had barriers to implementation which include: establishment of clinical utility, suitability for immobile patients and cost implication to GP practices.

conclusionThe development of a simple non-invasive clinical test to accelerate the diagnosis of heart failure in primary care maybe helpful to reduce unnecessary referrals to secondary care. The CORS test has the potential to serve this purpose; however, factors such as cost effectiveness, diagnostic accuracy and seamless implementation in primary care have to be fully explored.

Indexed as

AdultAttitude of Health PersonnelCardiac OutputExercise TestFemaleFocus GroupsHeart FailureHumansMaleMiddle AgedPatient SelectionPractice Patterns, Physicians'Primary Health CareQualitative Researchdiagnosisheart failureprimary carequalitative research

Identifiers

PMID30987993
PMCPMC6500186

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.