Evidence map›Paper›PMID 30987969›Full record

ArticleBlood advances2019

Mutations in the zebrafish

Jose A Hernandez, Victoria L Castro, Nayeli Reyes-Nava, Laura P Montes, Anita M Quintana

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  3. Using the Zebrafish as a Genetic Model to Study Erythropoiesis.International journal of molecular sciences · 2021
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jose A HernandezDepartment of Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX.
Victoria L CastroDepartment of Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX.
Nayeli Reyes-NavaDepartment of Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX.
Laura P MontesDepartment of Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX.
Anita M QuintanaDepartment of Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX.
The University of Texas at El Paso · US

Funding

TCCG12MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI KIRKEN, ROBERT A. · 2012 to 2018
$19.4M
Phase II of BUILDing SCHOLARSUL1GM118970 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$17.9M
RISE Scholars Program at UTEPR25GM069621 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J · 2004 to 2021
$11.2M
Phase II of BUILDing SCHOLARS - Student Training CoreTL4GM118971 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$9.9M
Phase II of BUILDing SCHOLARS - Research Enrichment CoreRL5GM118969 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$7.4M
Mutations in HCFC1 alter neural precursor differentiationK01NS099153 · NINDS · UNIVERSITY OF TEXAS EL PASO · PI QUINTANA, ANITA M · 2017 to 2019
$701k
NIGMS NIH HHS R25 GM069621NIGMS NIH HHS RL5 GM118969NIGMS NIH HHS TL4 GM118971NIGMS NIH HHS UL1 GM118970NIMHD NIH HHS G12 MD007592NINDS NIH HHS K01 NS099153
6 · The paper itself

Abstract

Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or thalassemia. The GATA1 transcription factor is an established mediator of RBC development. However, the upstream mechanisms that regulate the expression of

Indexed as

Hydroxymethylglutaryl-CoA SynthaseMutation, MissenseZebrafishAmino Acid SubstitutionAnimalsCell DifferentiationCholesterolErythrocytesErythropoiesisGATA1 Transcription FactorGene Expression RegulationTerpenesZebrafish ProteinsCholesterolgata1a protein, zebrafishGATA1 Transcription FactorHydroxymethylglutaryl-CoA SynthaseTerpenesZebrafish Proteins

Identifiers

PMID30987969
PMCPMC6482358
OpenAlexW2950060446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.