Evidence map›Paper›PMID 30987924›Full record

ArticleSchizophrenia research2019

Relationship between neuropsychological behavior and brain white matter in first-episode psychosis.

Andreia V Faria, Jeffrey Crawford, Chenfei Ye, Johnny Hsu, Anshel Kenkare, David Schretlen, Akira Sawa

Abstract read
In one paragraph

Article in Schizophrenia research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Brain regions associated with olfactory dysfunction in first episode psychosis patients.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Neuroimaging in schizophrenia: A review article.Frontiers in neuroscience · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andreia V FariaDepartment of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: afaria1@jhmi.edu.
Jeffrey CrawfordDepartment Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Chenfei YeDepartment of Electronics and Information, Harbin Institute of Technology Shenzhen Graduate School, Guangdong, China.
Johnny HsuDepartment of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Anshel KenkareDepartment Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
David SchretlenDepartment of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Akira SawaDepartment Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD, USA; Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.

Funding

Project 3P50MH094268 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SAWA, AKIRA · 2011 to 2020
$19.9M
High throughput marker for cognitive deficit: cellular autofluorescenceR01MH107730 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SAWA, AKIRA · 2018 to 2022
$3.0M
DISC1-dependent defects in neural fate, corticogenesis and cognition in psychosisR01MH105660 · NIMH · JOHNS HOPKINS UNIVERSITY · PI ISHIZUKA, KOKO, SAWA, AKIRA · 2014 to 2018
$2.8M
Oxidative stress and schizophrenia: combination of cell biology and brain imagingR01MH092443 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SAWA, AKIRA · 2011 to 2015
$1.8M
NIMH NIH HHS P50 MH094268NIMH NIH HHS R01 MH092443NIMH NIH HHS R01 MH105660NIMH NIH HHS R01 MH107730
6 · The paper itself

Abstract

We addressed the relationship between white matter architecture, represented by MRI fractional anisotropy (FA), and cognition in individuals with first-episode psychosis (FEP) by applying for a new methodology that allows whole brain parcellation of core and peripheral white matter in a biologically meaningful fashion. Regionally specific correlations were found in FEP between three specific domains of cognition (processing speed, attention/working memory, and executive functioning) and FA at the deep (cerebral peduncles, sagittal striatum, uncinate, internal/external capsule, cingulum) and peripheral white matter (adjacent to inferior temporal, angular, supramarginal, insula, occipital, rectus gyrus).

Indexed as

AdultCognitive DysfunctionCohort StudiesDiffusion Tensor ImagingFemaleHumansMalePsychotic DisordersSchizophreniaWhite MatterYoung AdultCognitionDTIFirst-episode psychosisMRISchizophrenia

Identifiers

PMID30987924
PMCPMC6544495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.