Evidence map›Paper›PMID 30987736›Full record

ArticleFertility and sterility2019

Female sleep patterns, shift work, and fecundability in a North American preconception cohort study.

Sydney Kaye Willis, Elizabeth Elliott Hatch, Amelia Kent Wesselink, Kenneth Jay Rothman, Ellen Margrethe Mikkelsen, Lauren Anne Wise

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fertility and sterility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 4 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sydney Kaye WillisDepartment of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts. Electronic address: siwillis@bu.edu.
Elizabeth Elliott HatchDepartment of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts.
Amelia Kent WesselinkDepartment of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts.
Kenneth Jay RothmanDepartment of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts; RTI International, Research Triangle Park, North Carolina.
Ellen Margrethe MikkelsenDepartment of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.
Lauren Anne WiseDepartment of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts.
Aarhus University · DKRTI International · US

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
Feasibility of an internet-based study of time-to-pregnancy in the United StatesR21HD072326 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WISE, LAUREN A · 2013 to 2014
$337k
NICHD NIH HHS R01 HD086742NICHD NIH HHS R21 HD072326
6 · The paper itself

Abstract

objectiveTo prospectively evaluate the association between female sleep patterns, shift work, and fecundability.

designWeb-based preconception cohort study, Pregnancy Study Online (PRESTO).

settingNot applicable. PATIENT(S): North American Women aged 21-45 years attempting pregnancy. INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): At baseline, self-reported average sleep duration per 24-hour period in the previous month, the frequency of trouble sleeping within the last 2 weeks (as measured by the Major Depression Inventory), and shift work patterns. Pregnancy status determined by follow-up questionnaires completed every 8 weeks for up to 12 months or until conception. RESULT(S): The analyses were restricted to 6,873 women attempting pregnancy for ≤6 months at enrollment from June 2013 through September 2018. We used proportional probabilities regression models to estimate fecundability ratios (FRs) and 95% confidence intervals (CIs), adjusting for potential confounders. Relative to 8 hours of sleep per day, FRs for <6, 6, 7, and ≥9 hours of sleep/day were 0.89 (95% CI, 0.75-1.06), 0.95 (95% CI, 0.86-1.04), 0.99 (95% CI, 0.92-1.06), and 0.96 (95% CI, 0.84-1.10), respectively. Compared with no trouble sleeping, FRs for trouble sleeping <50% of the time or trouble sleeping >50% of the time were 0.93 (95% CI, 0.88-1.00) and 0.87 (95% CI, 0.79-0.95), respectively. The results were slightly stronger among women with higher depressive symptoms and perceived stress levels. There was no association between shift work and fecundability. CONCLUSION(S): Trouble sleeping at night was associated with modestly reduced fecundability. A weaker inverse association was observed between shorter sleep duration and fecundability.

Indexed as

FertilityPersonnel Staffing and SchedulingSleepTime-to-PregnancyAdultFemaleHumansInfertility, FemaleMiddle AgedNorth AmericaProspective StudiesRisk AssessmentRisk FactorsSleep DeprivationSleep Disorders, Circadian RhythmSurveys and QuestionnairesCohort studiesfertilitypreconceptionsleeptime-to-pregnancy

Identifiers

PMID30987736
PMCPMC6546548
OpenAlexW2937103894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.