Evidence map›Paper›PMID 30987731›Full record

ArticleJournal of food and drug analysis2019

Analysis of heterocyclic amines in meat products by liquid chromatography - Tandem mass spectrometry.

Shi-Han Jian, Pei-Jou Yeh, Chung-Huang Wang, Hsin-Chang Chen, Sung-Fang Chen

Abstract read
In one paragraph

Article in Journal of food and drug analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shi-Han JianNational Taiwan Normal University, Department of Chemistry, Taiwan.
Pei-Jou YehNational Taiwan Normal University, Department of Chemistry, Taiwan.
Chung-Huang WangProduct and Process Research Center, Food Industry Research and Development, Taiwan.
Hsin-Chang ChenInstitute of Food Safety and Health, National Taiwan University, Taiwan.
Sung-Fang ChenNational Taiwan Normal University, Department of Chemistry, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterocyclic amines (HCAs), a class made up of more than 25 compounds, are unintended hazardous substances that are generated by the heating or processing of proteinaceous foods at high temperatures. The International Agency for Research on Cancer (IARC) has classified four such HCAs (IQ, MeIQ, MeIQx, and PhIP) as being probable or possible human carcinogens. In this study, two sample preparation strategies, liquid-liquid extraction (LLE) with solid-phase extraction (SPE) and a rapid, easy, cheap, effective, rugged, and safe extraction (QuEChERS) method, were investigated for the determination of 11 types of HCAs in meat products by LC-MS/MS. The HCAs in the samples were first extracted with acetonitrile by LLE, and followed by SPE. In the case of QuEChERS extraction, acetonitrile is used as the LLME solvent, and PSA, C18EC and MgSO

Indexed as

AminesAnimalsCattleChromatography, High Pressure LiquidHeterocyclic CompoundsLiquid-Liquid ExtractionMeat ProductsSwineTandem Mass SpectrometryAminesHeterocyclic CompoundsHeterocyclic aromatic aminesHPLC-MS/MSQuantitationQuEChERSSPE

Identifiers

PMID30987731
PMCPMC9296210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.