ArticleJournal of food and drug analysis2019
Using ambient mass spectrometry and LC-MS/MS for the rapid detection and identification of multiple illicit street drugs.
Article in Journal of food and drug analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 54 citations in OpenAlex.
- Permeably enclosed raw matrices direct analysis in real time mass spectrometry (PERM-DART-MS): a novel solution for the analysis of untreated samples.Analytical and bioanalytical chemistry · 2026Article
- Analysis of Drugs in Whole Blood by Paper Spray Mass Spectrometry with Integrated Solid-Phase Extraction.Analytical chemistry · 2025Article
- A systematic review of sensors to combat crime and routes to further sensor development.Frontiers in chemistry · 2025Review
- Study Rapid, Quantitative, and Simultaneous Detection of Drug Residues and Immunoassay in Chickens.Reviews on recent clinical trials · 2025Review
- Article
- Activity-based detection of synthetic cannabinoid receptor agonists in plant materials.Harm reduction journal · 2024Article
- Interpol Review of Drug Analysis 2019-2022.Forensic science international. Synergy · 2023Review
- From the Streets to the Judicial Evidence: Determination of Traditional Illicit Substances in Drug Seizures by a Rapid and Sensitive UHPLC-MS/MS-Based Platform.Molecules (Basel, Switzerland) · 2022Article
- Photoluminescent carbon nanomaterials for sensing of illicit drugs: focus.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2022Review
- A Study of Opiate, Opiate Metabolites and Antihistamines in Urine after Consumption of Cold Syrups by LC-MS/MS.Molecules (Basel, Switzerland) · 2020Article
- Interpol review of controlled substances 2016-2019.Forensic science international. Synergy · 2020Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study the recently developed technique of thermal desorption electrospray ionization/mass spectrometry (TD-ESI/MS) was applied to the rapid analysis of multiple controlled substances. With the reallocation of mass spectral resources [from a standard ESI source coupled with liquid chromatography (LC) to an ambient TD-ESI source], this direct-analysis technique allows the identification of a wider range of illicit drugs through a dual-working mode (pretreatment-free qualitative screening/conventional quantitative confirmation). Through 60-MRM (multiple reaction monitoring) analysis-in which the MS/MS process was programmed to sequentially scan 60 precursor ion/product ion transitions and, thereby, identify 30 compounds (two precursor/product ion transitions per compound)-of a four-component (drug) standard, the signal intensity ratios of each drug transition were comparable with those obtained through 8-MRM analysis, demonstrating the selectivity of TD-ESI/MS for the detection of multiple drugs. The consecutive analyses of tablets containing different active components occurred with no cross-contamination or interference from sample to sample, demonstrating the reliability of the TD-ESI/MS technique for rapid sampling (two samples min
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.