Evidence map›Paper›PMID 30987668›Full record

Trial reportJournal of the International Society of Sports Nutrition2019

Supplementation of eicosapentaenoic acid-rich fish oil attenuates muscle stiffness after eccentric contractions of human elbow flexors.

Yosuke Tsuchiya, Kenichi Yanagimoto, Hisashi Ueda, Eisuke Ochi

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Effects of LCNutrients · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yosuke TsuchiyaFaculty of Modern life, Teikyo Heisei University, Tokyo, Japan.
Kenichi YanagimotoFood Function R&D Center, Nippon Suisan Kaisha, Ltd., Tokyo, Japan.
Hisashi UedaFaculty of Health and Medical Science, Teikyo Heisei University, Chiba, Japan.
Eisuke OchiFaculty of Bioscience and Applied Chemistry, Hosei University, 3-7-2, Kajino, Koganei, Tokyo, Japan. ochi@hosei.ac.jp.ORCID http://orcid.org/0000-0002-2497-0250
Teikyo Heisei University · JPHosei University · JPNippon Suisan Kaisha (Japan) · JP

Funding

Nippon Suisan Kaisha Ltd. N/A
6 · The paper itself

Abstract

backgroundThis study aimed to investigate the effect of supplementation of fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the damage of the biceps brachii after eccentric contractions (ECCs) of the elbow flexors, particularly focusing on muscle stiffness.

methodsSixteen men were included in this double-blind, placebo-controlled, parallel design study and the participants were randomly assigned to the EPA and DHA supplement group (EPA, n = 8) and placebo group (PL, n = 8). They consumed either EPA 600 mg and DHA 260 mg per day or placebo supplement for 8 weeks prior to exercise. Moreover, they performed six sets of 10 ECCs at 100% maximal voluntary contraction (MVC) using a dumbbell. Changes in MVC torque, range of motion (ROM), upper arm circumference, muscle soreness, muscle echo intensity, and muscle stiffness were assessed before exercise; immediately after exercise; and 1, 2, and 5 days after exercise.

resultsMVC torque and ROM were significantly higher in the EPA group than in the PL group after ECCs (p < 0.05). Muscle soreness, upper arm circumference, and muscle echo intensity were significantly higher in the PL group than in the EPA group after ECCs (p < 0.05). In addition, muscle stiffness at 150° was significantly higher in the PL group than in the EPA group immediately after ECCs (p < 0.05).

conclusionThe present study showed that EPA and DHA supplementation has a positive role in inhibiting muscle stiffness after ECCs.

trial registrationThis trial (UMIN000028165) was registered on 10th/July/2017.

Indexed as

Docosahexaenoic AcidsDouble-Blind MethodEicosapentaenoic AcidElbowFish OilsHumansIsometric ContractionMaleMuscle, SkeletalMyalgiaRange of Motion, ArticularTorqueYoung AdultDocosahexaenoic AcidsEicosapentaenoic AcidFish OilsEcho intensityEicosapentaenoic acidMuscle functionMuscle sorenessMuscle swellingOmega-3 polyunsaturated fatty acidsShear elastic modulusShear wave elastography

Identifiers

PMID30987668
PMCPMC6466674
OpenAlexW2938370864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.