Evidence map›Paper›PMID 30987582›Full record

Observational studyBMC cardiovascular disorders2019

Unique electrocardiographic pattern "w" wave in lead I of idiopathic ventricular arrhythmias arising from the distal great cardiac vein.

Teng Li, Qiong Xu, Xian-Zhang Zhan, Yu-Mei Xue, Hong-Tao Liao, Yi-Fu Li, Konstantinos P Letsas, Shu-Lin Wu

Open access · goldAbstract readObservational StudyVideo-Audio Media
In one paragraph

Observational study in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Teng LiArrhythmia Department, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, 518057, Guangdong, China.
Qiong XuArrhythmia Department, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, 518057, Guangdong, China.
Xian-Zhang ZhanCardiovascular Department, Guangdong Cardiovascular Institute, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, 510010, Guangdong, China.
Yu-Mei XueCardiovascular Department, Guangdong Cardiovascular Institute, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, 510010, Guangdong, China.
Hong-Tao LiaoCardiovascular Department, Guangdong Cardiovascular Institute, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, 510010, Guangdong, China.
Yi-Fu LiArrhythmia Department, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, 518057, Guangdong, China.
Konstantinos P LetsasSecond Department of Cardiology, Laboratory of Cardiac Electrophysiology, Evangelismos General Hospital of Athens, Athens, Greece.
Shu-Lin WuCardiovascular Department, Guangdong Cardiovascular Institute, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, 510010, Guangdong, China. doctorwushulin@163.com.ORCID 0000-0003-0684-934X
Guangdong General Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNEvangelismos Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ECG characteristics of the distal coronary venous system ventricular arrhythmias (VAs) share common features with VAs arising from the aortic cusps or the endocardial left ventricular outflow tract (LVOT) beneath the cusps. The purpose of this study was to identify specific electrocardiographic and electrophysiological characteristics of VAs originating from the distal great cardiac vein (GCV).

methodsBased on the successful ablation site, patients with idiopathic VAs from the distal GCV, left coronary cusp (LCC) or the subvalvular left ventricular outflow tract (LVOT) area were included in the present study.

resultsThe final population consisted of 39 patients (35 males, mean age 51 ± 23 years). All VAs displayed a right bundle branch block (RBBB) morphology with inferior axis. Among these patients, 15 were successfully ablated at the GCV, 15 at the LCC and 9 at the subvalvular region. A "w" pattern in lead I was present in 12 out of 15 (80%) VAs originating from the distal GCV compared to none of VAs arising from the other two sites (p < 0.01). VAs with a GCV origin exhibited more commonly increased intrinsicoid deflection time, higher maximum deflection index and wider QRS duration compared to LCC and subvalvular sites (p < 0.05). Acceptable pace mapping at the successful ablation site was achieved in 10 patients. After an average of 36 ± 24 months follow up, 14 (93.3%) patients were free from VAs recurrence.

conclusionA "w" pattern in lead I may distinguish distal GCV VAs from VAs arising from the LCC or the subvalvular region.

Indexed as

Action PotentialsElectrocardiographyAdultAgedArrhythmias, CardiacBundle-Branch BlockCatheter AblationCoronary SinusElectrophysiologic Techniques, CardiacFemaleHeart RateHeart VentriclesHumansMaleMiddle AgedPredictive Value of TestsCatheter ablationGreat cardiac veinIdiopathicVentricular arrhythmias

Identifiers

PMID30987582
PMCPMC6466655
OpenAlexW2946509019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.