Evidence map›Paper›PMID 30987375›Full record

ArticleCancers2019

Membrane Lipidome Reorganization and Accumulation of Tissue DNA Lesions in Tumor-Bearing Mice: An Exploratory Study.

Marios G Krokidis, Maria Louka, Eleni K Efthimiadou, Sevasti-Kiriaki Zervou, Kyriakos Papadopoulos, Anastasia Hiskia, Carla Ferreri, Chryssostomos Chatgilialoglu

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  5. Spectroscopic and in vitro Investigations of FeChembiochem : a European journal of chemical biology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Marios G KrokidisInstitute of Nanoscience and Nanotechnology, N.C.S.R. "Demokritos", 15310 Agia Paraskevi-Athens, Greece. m.krokidis@inn.demokritos.gr.
Maria LoukaLipidomics Laboratory, Lipinutragen srl, Via Piero Gobetti 101, 40129 Bologna, Italy. mar_louka@yahoo.gr.
Eleni K EfthimiadouInstitute of Nanoscience and Nanotechnology, N.C.S.R. "Demokritos", 15310 Agia Paraskevi-Athens, Greece. e.efthimiadou@inn.demokritos.gr.
Sevasti-Kiriaki ZervouInstitute of Nanoscience and Nanotechnology, N.C.S.R. "Demokritos", 15310 Agia Paraskevi-Athens, Greece. s.zervou@inn.demokritos.gr.
Kyriakos PapadopoulosInstitute of Nanoscience and Nanotechnology, N.C.S.R. "Demokritos", 15310 Agia Paraskevi-Athens, Greece. k.papadopoulos@inn.demokritos.gr.
Anastasia HiskiaInstitute of Nanoscience and Nanotechnology, N.C.S.R. "Demokritos", 15310 Agia Paraskevi-Athens, Greece. a.hiskia@inn.demokritos.gr.
Carla FerreriLipidomics Laboratory, Lipinutragen srl, Via Piero Gobetti 101, 40129 Bologna, Italy. carla.ferreri@isof.cnr.it.
Chryssostomos ChatgilialogluInstitute of Nanoscience and Nanotechnology, N.C.S.R. "Demokritos", 15310 Agia Paraskevi-Athens, Greece. chrys@isof.cnr.it.
National Centre of Scientific Research "Demokritos" · GRInstitute of Organic Synthesis and Photoreactivity · ITNational and Kapodistrian University of Athens · GR

Funding

Horizon 2020 Framework Programme MSCAETN-2014-642023Program "Establishing a Multidisciplinary and Effective Innovation and Entrepreneurship Hub" GGET/SIEMENS
6 · The paper itself

Abstract

Increased rates of reactive oxygen/nitrogen species (ROS/RNS) are involved in almost all cancer types, associated with tumor development and progression, causing damage to biomolecules such as proteins, nucleic acids and membrane lipids, in different biological compartments. We used a human tumor xenograft mouse model to evaluate for the first time in parallel the remodeling of fatty acid moieties in erythrocyte membrane phospholipids and the level of ROS-induced DNA lesions in liver and kidney tissues. Using liquid chromatography tandem mass spectrometry the 5'

Indexed as

fatty acid-based lipidomicsgenotoxic stressmembrane phospholipidsoxidative lesionstumor-bearing mice

Identifiers

PMID30987375
PMCPMC6520748
OpenAlexW2931837038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.