ReviewHealthcare (Basel, Switzerland)2019
Blockchain Technology in Healthcare: A Systematic Review.
Review in Healthcare (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
125 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Securing Federated Learning With Blockchain in the Medical Field: Systematic Literature Review.Journal of medical Internet research · 2026Pooled it
- Blockchain in Health Information Systems: A Systematic Review.International journal of environmental research and public health · 2024Pooled it
- Biomedical blockchain with practical implementations and quantitative evaluations: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2024Pooled it
- Non-fungible tokens (NFTs) in healthcare: a thematic analysis and research agenda.Frontiers in digital health · 2024Pooled it
- Blockchain technology in healthcare: A systematic review.PloS one · 2022Pooled it
- Blockchain applications in health care for COVID-19 and beyond: a systematic review.The Lancet. Digital health · 2021Pooled it
- Blockchain Personal Health Records: Systematic Review.Journal of medical Internet research · 2021Pooled it
- The Current State of Research, Challenges, and Future Research Directions of Blockchain Technology in Patient Care: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Universal immunization program in India: a review of childhood vaccine updates over the last decade (2014-2024).IJID regions · 2026Review
- Blockchain for cross-border pandemic surveillance: solving the "Data Silo" problem in global health security.Annals of medicine and surgery (2012) · 2026Article
- Patient Perceptions and Acceptance of Blockchain-Based Health Data Sharing in Oncology: Cross-Sectional Survey.JMIR formative research · 2026Article
- Artificial Intelligence in Peripheral Artery Disease: A Science Advisory From the American Heart Association.Circulation. Population health and outcomes · 2026Review
- Resistance to Blockchain Adoption in Health Care Organizations: Evidence From a Cross-Sectional Study.Journal of medical Internet research · 2026Article
- Comparing decentralized machine learning and AI clinical models to local and centralized alternatives: a systematic review.NPJ digital medicine · 2026Article
- A hybrid blockchain migration framework for converting traditional databases into blockchain-based EMR systems.Scientific reports · 2026Article
- Assessment of Blockchain Technology in the Improvement of Supply Chain Management in the Pharmaceutical Industry.Recent patents on biotechnology · 2026Review
- Quantum Threats to Bitcoin, Cryptocurrency and Blockchain.Blockchain in healthcare today · 2026Article
- CITADEL: a post-quantum secure blockchain framework for privacy-preserving electronic health records with temporally-partitioned federated learning.Frontiers in artificial intelligence · 2026Article
- A Blockchain-Based Architecture for Dynamic and Auditable Patient Consent in Secondary Use of Health Data.Blockchain in healthcare today · 2026Article
- AI-Guided Discovery of Oncogenic Signaling Crosstalk in Tumor Progression and Drug Resistance.Oncology research · 2026Review
65 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since blockchain was introduced through Bitcoin, research has been ongoing to extend its applications to non-financial use cases. Healthcare is one industry in which blockchain is expected to have significant impacts. Research in this area is relatively new but growing rapidly; so, health informatics researchers and practitioners are always struggling to keep pace with research progress in this area. This paper reports on a systematic review of the ongoing research in the application of blockchain technology in healthcare. The research methodology is based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and a systematic mapping study process, in which a well-designed search protocol is used to search four scientific databases, to identify, extract and analyze all relevant publications. The review shows that a number of studies have proposed different use cases for the application of blockchain in healthcare; however, there is a lack of adequate prototype implementations and studies to characterize the effectiveness of these proposed use cases. The review further highlights the state-of-the-art in the development of blockchain applications for healthcare, their limitations and the areas for future research. To this end, therefore, there is still the need for more research to better understand, characterize and evaluate the utility of blockchain in healthcare.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.