Evidence map›Paper›PMID 30987317›Full record

ArticleToxins2019

A New Topical Eye Drop Containing LyeTxI-b, A Synthetic Peptide Designed from A

Carolina Nunes da Silva, Flavia Rodrigues da Silva, Lays Fernanda Nunes Dourado, Pablo Victor Mendes Dos Reis, Rummenigge Oliveira Silva, Bruna Lopes da Costa, Paula Santos Nunes, Flávio Almeida Amaral, Vera Lúcia Dos Santos, Maria Elena de Lima and 1 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Artificial intelligence catalyzes antimicrobial peptide design.Synthetic and systems biotechnology · 2027
    Review
  2. Comparative Structural and Biophysical Investigation ofAntibiotics (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Journal of clinical medicine · 2021
    Review
  8. Shortened derivatives from native antimicrobial peptide LyeTx I:Experimental biology and medicine (Maywood, N.J.) · 2021
    Article
  9. Synthetic Peptides Derived FromFrontiers in molecular biosciences · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Non-antibiotic management of bacterial keratitis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Carolina Nunes da SilvaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. carolinnanunes@yahoo.com.br.ORCID 0000-0003-1382-2487
Flavia Rodrigues da SilvaPrograma de Pós-Graduação em Ciências Aplicadas à Saúde-PPGCAS, Universidade Federal de Sergipe, Lagarto 49400-000 SE, Brazil. dra.flaviarodrigues@hotmail.com.ORCID 0000-0003-3007-9795
Lays Fernanda Nunes DouradoFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. laysndourado@gmail.com.ORCID 0000-0001-5287-455X
Pablo Victor Mendes Dos ReisDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. reispvm@gmail.com.ORCID 0000-0001-9030-1015
Rummenigge Oliveira SilvaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. rummeniggeita@gmail.com.
Bruna Lopes da CostaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. brunalc1991@gmail.com.ORCID 0000-0002-6513-0717
Paula Santos NunesPrograma de Pós-Graduação em Ciências Aplicadas à Saúde-PPGCAS, Universidade Federal de Sergipe, Lagarto 49400-000 SE, Brazil. paulanunes_se@yahoo.com.br.ORCID 0000-0003-3588-0178
Flávio Almeida AmaralDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. dr.famaral@gmail.com.ORCID 0000-0002-1695-0612
Vera Lúcia Dos SantosDepartamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. verabio@gmail.com.
Maria Elena de LimaPrograma de Pós-graduação em Ciências da Saúde, Biomedicina e Medicina, Ensino e Pesquisa da Santa Casa de Belo Horizonte, Grupo Santa Casa de Belo Horizonte, Belo Horizonte 30150-250, MG, Brazil. mariaelena@santacasabh.org.br.
Armando da Silva Cunha JúniorFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901 MG, Brazil. armando@farmacia.ufmg.br.ORCID 0000-0002-1161-8936
Universidade Federal de Minas Gerais · BRUniversidade Federal de Sergipe · BRGrupo Santa Casa de Belo Horizonte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial keratitis is an ocular infection that can lead to severe visual disability.

Indexed as

Administration, TopicalAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesArthropod ProteinsChickensChorioallantoic MembraneEyeEye Infections, BacterialFemaleKeratitisNeutrophilsOphthalmic SolutionsRabbitsSpider VenomsStaphylococcal InfectionsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesArthropod ProteinsLyeTx I protein, Lycosa erythrognathaOphthalmic SolutionsSpider VenomskeratitisLyeTxI-bStaphylococcus aureus

Identifiers

PMID30987317
PMCPMC6520776
OpenAlexW2927287711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.