Evidence map›Paper›PMID 30987261›Full record

ArticleCancers2019

Unlocking the Potential of Saliva-Based Test to Detect HPV-16-Driven Oropharyngeal Cancer.

Kai Dun Tang, Kurt Baeten, Liz Kenny, Ian H Frazer, Gert Scheper, Chamindie Punyadeera

Abstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Screening for oropharyngeal cancer: the time is now.Expert review of molecular diagnostics · 2025
    Article
  5. Salivary biomarkers: a promising approach for predicting immunotherapy response in head and neck cancers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  6. Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care.International journal of environmental research and public health · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. An Exploratory Study Demonstrating That Salivary Cytokine Profiles Are Altered in Children With Small Area Thermal Injury.Journal of burn care & research : official publication of the American Burn Association · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kai Dun TangThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology and the Translational Research Institute, Queensland 4059, Australia. kai.tang@qut.edu.au.
Kurt BaetenJanssen Diagnostics, Janssen Pharmaceutica NV, Beerse 2340, Belgium. KBAETEN1@its.jnj.com.
Liz KennySchool of Medicine, University of Queensland, Queensland 4029, Australia. lizkenny@bigpond.net.au.
Ian H FrazerFaculty of Medicine, The University of Queensland, Translational Research Institute, Queensland 4102, Australia. i.frazer@uq.edu.au.
Gert ScheperJanssen Vaccines & Prevention BV, Leiden 2333, The Netherlands. GSCHEPER@its.jnj.com.
Chamindie PunyadeeraThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology and the Translational Research Institute, Queensland 4059, Australia. chamindie.punyadeera@qut.edu.au.

Funding

Janssen: Pharmaceutical Companies of Johnson & Johnson NAQueensland Centre for Head and Neck funded by Atlantic Philanthropies, the Queensland Government NA
6 · The paper itself

Abstract

The incidence of human papillomavirus (HPV)-positive oropharyngeal cancer (OPC) is rising in high-income countries, including Australia. Increasing evidence suggests that accurate HPV testing is pivotal for clinical decision making and treatment planning in these patients. Recently, the eighth edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) tumor-node-metastasis (TNM) staging system for OPC (based on the p16INK4a (p16) status) was proposed and has been implemented. However, the applicability of this new staging system is still far from clear. In our study,

Indexed as

HPV-16 integrationHPV-16 viral loadhuman papillomavirusoropharyngeal cancersaliva

Identifiers

PMID30987261
PMCPMC6521163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.