ArticleNutrients2019
Relationship between the Intake of n-3 Polyunsaturated Fatty Acids and Depressive Symptoms in Elderly Japanese People: Differences According to Sex and Weight Status.
Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Effect of High Ratio of n-6/n-3 PUFAs on Depression: A Meta-Analysis of Prospective Studies.Frontiers in nutrition · 2022Pooled it
- Relationship between objective sleep efficiency and psychological distress in middle-aged and older Japanese: Results by work in the Shika study.BMC psychology · 2026Article
- Impact of eating alone and nutrient intake on psychological distress among older Japanese adults: A cross-sectional study.Asia Pacific journal of clinical nutrition · 2025Article
- Mental health in society's margins: poorThe British journal of nutrition · 2024Article
- Sex differences in erythrocyte fatty acid composition of first-diagnosed, drug-naïve patients with major depressive disorders.Frontiers in pharmacology · 2023Article
- Association between dietary theobromine with depression: a population-based study.BMC psychiatry · 2022Article
- Relationship between Vitamin Intake and Resilience Based on Sex in Middle-Aged and Older Japanese Adults: Results of the Shika Study.Nutrients · 2022Article
- Hypertension and Low Body Weight Are Associated with Depressive Symptoms Only in Females: Findings from the Shika Study.Behavioral sciences (Basel, Switzerland) · 2022Article
- Association between Dietary Fat Intake and Hyperuricemia in Men with Chronic Kidney Disease.Nutrients · 2022Article
- Relationship between Decreased Mineral Intake Due to Oral Frailty and Bone Mineral Density: Findings from Shika Study.Nutrients · 2021Article
- Relationship between Vitamin Intake and Health-Related Quality of Life in a Japanese Population: A Cross-Sectional Analysis of the Shika Study.Nutrients · 2021Article
- Protein intake in inhabitants with regular exercise is associated with sleep quality: Results of the Shika study.PloS one · 2021Article
- A New Social Network Scale for Detecting Depressive Symptoms in Older Japanese Adults.International journal of environmental research and public health · 2020Article
- Behavioral, neuromorphological, and neurobiochemical effects induced by omega-3 fatty acids following basal forebrain cholinergic depletion in aged mice.Alzheimer's research & therapy · 2020Article
- Neuroprotective Role of Dietary Supplementation with Omega-3 Fatty Acids in the Presence of Basal Forebrain Cholinergic Neurons Degeneration in Aged Mice.International journal of molecular sciences · 2020Article
- Associations of n-3, n-6 Fatty Acids Intakes and n-6:n-3 Ratio with the Risk of Depressive Symptoms: NHANES 2009-2016.Nutrients · 2020Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
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Abstract
n-3 polyunsaturated fatty acids (PUFAs) have been shown to have preventive effects against depression. In this study, we aimed to investigate the associations between the intake of n-3 PUFAs and depression among people according to sex and weight status. We utilized cross-sectional data from the Shika study in Japan. The study was conducted between 2013 and 2016. Data were collected from adults older than 65 years. Invitation letters were distributed to 2677 individuals, 2470 of whom participated in the study (92.3%). We assessed depressive states using the Japanese short version of the Geriatric Depression Scale (GDS-15). We assessed the intake of n-3 PUFAs using the validated food frequency questionnaire. One thousand six hundred thirty-three participants provided data, among which 327 (20.0%) exhibited depressive symptoms. When we performed the stratified analysis by sex and weight status, there were significant inverse relationships between total n-3 PUFAs, individual n-3 PUFAs, and n-3/n-6 PUFAs ratio and depressive symptoms in overweight/obese females. No correlations were observed between n-3 PUFAs intake and depressive states in males. The results demonstrated a relationship between n-3 PUFAs deficiencies and depressive states, particularly in overweight/obese females. Dietary modifications may help to prevent depressive symptoms in overweight/obese females.
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