Evidence map›Paper›PMID 30987180›Full record

ArticleMetabolites2019

The Effect of Pre-Analytical Conditions on Blood Metabolomics in Epidemiological Studies.

Diana L Santos Ferreira, Hannah J Maple, Matt Goodwin, Judith S Brand, Vikki Yip, Josine L Min, Alix Groom, Debbie A Lawlor, Susan Ring

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Diana L Santos FerreiraMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. diana.santosferreira@bristol.ac.uk.ORCID 0000-0001-8923-0117
Hannah J MapleMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. hannah.maple@bio-techne.com.
Matt GoodwinMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. matt.goodwin@bristol.ac.uk.ORCID 0000-0001-9655-6465
Judith S BrandMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. judith.brand@bristol.ac.uk.
Vikki YipPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PS, UK. vikki.yip@bristol.ac.uk.
Josine L MinMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. josine.min@bristol.ac.uk.ORCID 0000-0003-4456-9824
Alix GroomMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. alix.groom@bristol.ac.uk.
Debbie A LawlorMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. d.a.lawlor@bristol.ac.uk.
Susan RingMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK. s.m.ring@bristol.ac.uk.ORCID 0000-0003-3103-9330
University of Bristol · GBÖrebro University · SE

Funding

Cohorts and Longitudinal Studies Enhancement Resources ES/K000357/1Medical Research Council G1001799Medical Research Council MC_UU_00011/6Medical Research Council MR/P023444/1UK Medical Research Council MC_UU_00011/6UK National Institute of Health Research Senior Investigator NF-SI-0166-10196
6 · The paper itself

Abstract

Serum and plasma are commonly used in metabolomic-epidemiology studies. Their metabolome is susceptible to differences in pre-analytical conditions and the impact of this is unclear. Participant-matched EDTA-plasma and serum samples were collected from 37 non-fasting volunteers and profiled using a targeted nuclear magnetic resonance (NMR) metabolomics platform (

Indexed as

metabolomicsnuclear magnetic resonanceplasmapre-analytical phaseserum

Identifiers

PMID30987180
PMCPMC6523923
OpenAlexW2908727532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.