Evidence map›Paper›PMID 30987179›Full record

ArticleMolecules (Basel, Switzerland)2019

Discovery of Novel Triazole-Containing Pyrazole Ester Derivatives as Potential Antibacterial Agents.

Ming-Jie Chu, Wei Wang, Zi-Li Ren, Hao Liu, Xiang Cheng, Kai Mo, Li Wang, Feng Tang, Xian-Hai Lv

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Recent Development of DNA Gyrase Inhibitors: An Update.Mini reviews in medicinal chemistry · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming-Jie ChuSchool of Science, Anhui Agricultural University, Hefei 230036, China. chumingjie@ahau.edu.cn.
Wei WangSchool of Science, Anhui Agricultural University, Hefei 230036, China. weiwang133@163.com.
Zi-Li RenSchool of Science, Anhui Agricultural University, Hefei 230036, China. renzilix@163.com.
Hao LiuSchool of Science, Anhui Agricultural University, Hefei 230036, China. 13167720906@163.com.
Xiang ChengSchool of Science, Anhui Agricultural University, Hefei 230036, China. xiangcheng215b@163.com.
Kai MoSchool of Science, Anhui Agricultural University, Hefei 230036, China. 18256549679@163.com.
Li WangSchool of Science, Anhui Agricultural University, Hefei 230036, China. Wangli-hx@ahau.edu.cn.
Feng TangInternational Center for Bamboo and Rattan, 8 Fu Tong East Street, Beijing 100714, China. fengtang@icbr.ac.cn.
Xian-Hai LvSchool of Science, Anhui Agricultural University, Hefei 230036, China. lvxianhai@ahau.edu.cn.

Funding

National Key R&D Program of China 2017YFD0600805Natural Science Foundation of Anhui Province KJ2018A0162The Basic Science Research Fund Program of ICBR 1632017005
6 · The paper itself

Abstract

To develop new antibacterial agents, a series of novel triazole-containing pyrazole ester derivatives were designed and synthesized and their biological activities were evaluated as potential topoisomerase II inhibitors. Compound

Indexed as

Anti-Bacterial AgentsDNA GyraseEstersMicrobial Sensitivity TestsMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructurePyrazolesStructure-Activity RelationshipTopoisomerase II InhibitorsTriazolesAnti-Bacterial AgentsDNA GyraseEsterspyrazolePyrazolesTopoisomerase II InhibitorsTriazolesantibacterialesterpyrazoletopoisomerase II inhibitortriazole

Identifiers

PMID30987179
PMCPMC6480153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.