Evidence map›Paper›PMID 30987022›Full record

ArticleGenes2019

An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats.

Yuan Y Zheng, Sheng D Sheng, Tai Y Hui, Chang Yue, Jia M Sun, Dan Guo, Su L Guo, Bo J Li, Hui L Xue, Ze Y Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Genome-wide selective sweep analysis in high-altitude Changthangi goats reveals candidate genes for pashmina fiber production.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  3. Article
  4. Article
  5. Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yuan Y ZhengCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. zhengyuanyuan07@163.com.
Sheng D ShengCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. ssda111@126.com.
Tai Y HuiCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. huitaiyu0529@163.com.
Chang YueCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. 15909826217@163.com.
Jia M SunCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. s541524030@163.com.
Dan GuoAnimal Genetic Breeding, Academy of Animal Husbandry Science of Liaoning Province, Liaoyang 130062, China. dan810308@163.com.
Su L GuoProsperous Community, Changshun Town, Huade 013350, China. 17824229545@163.com.
Bo J LiCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. libojiang12@126.com.
Hui L XueCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. huilingxue_2002@126.com.
Ze Y WangCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. wangzeying2012@syau.edu.cn.
Wen L BaiCollege of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. baiwenlin55@163.com.
Shenyang Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal growth and development are regulated by long non-coding RNAs (lncRNAs). However, the functions of lncRNAs in regulating cashmere fineness are poorly understood. To identify the key lncRNAs that are related to cashmere fineness in skin, we have collected skin samples of Liaoning cashmere goats (LCG) and Inner Mongolia cashmere goats (MCG) in the anagen phase, and have performed RNA sequencing (RNA-seq) approach on these samples. The high-throughput sequencing and bioinformatics analyses identified 437 novel lncRNAs, including 93 differentially expressed lncRNAs. We also identified 3,084 differentially expressed messenger RNAs (mRNAs) out of 27,947 mRNAs. Gene ontology (GO) analyses of lncRNAs and target genes in cis show a predominant enrichment of targets that are related to intermediate filament and intermediate filament cytoskeleton. According to the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, sphingolipid metabolism is a significant pathway for lncRNA targets. In addition, this is the first report to reveal the possible lncRNA-mRNA regulatory network for cashmere fineness in cashmere goats. We also found that lncRNA XLOC_008679 and its target gene, KRT35, may be related to cashmere fineness in the anagen phase. The characterization and expression analyses of lncRNAs will facilitate future studies on the potential value of fiber development in LCG.

Indexed as

AnimalsComputational BiologyGene Regulatory NetworksGoatsHair FollicleHigh-Throughput Nucleotide SequencingLipid MetabolismMicroRNAsRNA, Long NoncodingRNA, MessengerSkinMicroRNAsRNA, Long NoncodingRNA, Messengercashmere finenessdifferently expressed geneslncRNAlncRNA–targetsRNA-seq

Identifiers

PMID30987022
PMCPMC6523453
OpenAlexW2933601889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.