Evidence map›Paper›PMID 30987011›Full record

ArticlePharmaceutics2019

Melt-Cast Films Significantly Enhance Triamcinolone Acetonide Delivery to the Deeper Ocular Tissues.

Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Bhavik Soneta, Bharathi Avula, Soumyajit Majumdar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Akshaya TatkeDepartment of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. aatatke@go.olemiss.edu.
Narendar DudhipalaDepartment of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. ndudhipa@olemiss.edu.
Karthik Yadav JangaDepartment of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. kjanga@go.olemiss.edu.
Bhavik SonetaDepartment of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. bksoneta@go.olemiss.edu.
Bharathi AvulaResearch Institute of Pharmaceutical Sciences, The University of Mississippi, Oxford, MS 38677, USA. bavula@olemiss.edu.
Soumyajit MajumdarDepartment of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA. majumso@olemiss.edu.
University of Mississippi · US

Funding

Evaluation and Inhibition of Efflux Pumps Expressed on the Blood Ocular BarrierR01EY022120 · NEI · UNIVERSITY OF MISSISSIPPI · PI MAJUMDAR, SOUMYAJIT · 2015 to 2018
$1.5M
NEI NIH HHS 1R01EY022120NEI NIH HHS R01 EY022120NIH HHS 1R01EY022120
6 · The paper itself

Abstract

Delivering an effective drug load to the posterior section of the ocular tissues, while using a non-invasive technique, has always been a challenge. In this regard, the goal of the present study was to develop sustained release triamcinolone acetonide (TA) loaded polymeric matrix films for ocular delivery. The TA-films were prepared in two different polymer matrices, with drug loadings of 10% and 20%

Indexed as

in vitro releasemelt-castocular distributionPEOpermeabilitySoluplus®Triamcinolone acetonide

Identifiers

PMID30987011
PMCPMC6523835
OpenAlexW2929927002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.