Evidence map›Paper›PMID 30986928›Full record

ArticleMolecules (Basel, Switzerland)2019

Investigating the Influence of Steric Hindrance on Selective Anion Transport.

Laura A Jowett, Angela Ricci, Xin Wu, Ethan N W Howe, Philip A Gale

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Synthesis of Novel Anion Recognition Molecules as Quinazoline Precursors.International journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Tetrapodal Anion Transporters.Molecules (Basel, Switzerland) · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura A JowettSchool of Chemistry (F11), The University of Sydney, Sydney, NSW 2006, Australia. ljow8193@uni.sydney.edu.au.
Angela RicciChemistry, University of Southampton, Southampton SO17 1BJ, UK. angela.ricci20@gmail.com.
Xin WuSchool of Chemistry (F11), The University of Sydney, Sydney, NSW 2006, Australia. xin.wu@sydney.edu.au.
Ethan N W HoweSchool of Chemistry (F11), The University of Sydney, Sydney, NSW 2006, Australia. ethan.howe@sydney.edu.au.
Philip A GaleSchool of Chemistry (F11), The University of Sydney, Sydney, NSW 2006, Australia. philip.gale@sydney.edu.au.ORCID 0000-0001-9751-4910

Funding

Australian Research Council DP180100612Engineering and Physical Sciences Research Council EP/J009687/1
6 · The paper itself

Abstract

A series of symmetrical and unsymmetrical alkyl tren based tris-thiourea anion transporters were synthesised and their anion binding and transport properties studied. Overall, increasing the steric bulk of the substituents resulted in improved chloride binding and transport abilities. Including a macrocycle in the scaffold enhanced the selectivity of chloride transport in the presence of fatty acids, by reducing the undesired H⁺ flux facilitated by fatty acid flip-flop. This study demonstrates the benefit of including enforced steric hindrance and encapsulation in the design of more selective anion receptors.

Indexed as

AnionsChloridesIon TransportLipid BilayersMagnetic Resonance SpectroscopyModels, MolecularThioureaAnionsChloridesLipid BilayersThioureaanion transportlipid bilayerthioureas

Identifiers

PMID30986928
PMCPMC6480120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.