Evidence map›Paper›PMID 30986729›Full record

SynthesisEuropean psychiatry : the journal of the Association of European Psychiatrists2019

Emotion dysregulation and non-suicidal self-injury: A systematic review and meta-analysis.

Jennifer C Wolff, Elizabeth Thompson, Sarah A Thomas, Jacqueline Nesi, Alexandra H Bettis, Briana Ransford, Katie Scopelliti, Elisabeth A Frazier, Richard T Liu

2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European psychiatry : the journal of the Association of European Psychiatrists, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 215 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
215citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05343039 nacompletednot on this mapstarted 2022, after this paper: background citation

Leveraging Biomarkers and New Technologies to Reduce Self-Injury and Substance Abuse Risk Among Highly Vulnerable Adolescents

TypeinterventionalSponsorUniversity of Notre DameRan2022 to 2025Enrolled30ConditionsNonsuicidal Self Injury, Alcohol Abuse, Vagus Nerve StimulationArmsNon-invasive Transcutaneous Nerve Stimulation (tVNS), No Intervention
NCT06025942 nacompletednot on this mapstarted 2024, after this paper: background citation

Enhancing Emotion Regulation With an In-situ Socially Assistive Robot Among LGBTQ+ Youth With Self-harm Ideation: a Randomised Control Trial

TypeinterventionalSponsorKing's College LondonRan2024 to 2025Enrolled155ConditionsEmotion Regulation, Self HarmArmsPurrble intervention
3 · Its place in the literature

Who cites it

215 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  10. [Efficacy evaluation of repeated transcranial magnetic stimulation combined with bipolar depression triple therapy in reducing female adolescents' non-suicidal self-injury].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
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155 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer C WolffThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States. Electronic address: jennifer_wolff@brown.edu.
Elizabeth ThompsonThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.
Sarah A ThomasThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.
Jacqueline NesiThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.
Alexandra H BettisThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.
Briana RansfordThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.
Katie ScopellitiThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.
Elisabeth A FrazierThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.
Richard T LiuThe Alpert Medical School of Brown University, 1 Hoppin St, Suite 204, 02093, Providence, RI, United States.

Funding

RESEARCH TRAINING IN CHILD MENTAL HEALTHT32MH019927 · NIMH · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI Kristen G Benito, Anthony Spirito · 1994 to 2026
$7.8M
Training in Child/Adolescent Biobehavioral HIV ResearchT32MH078788 · NIMH · RHODE ISLAND HOSPITAL · PI LARRY K BROWN · 2007 to 2026
$6.2M
NIMH NIH HHS T32 MH019927NIMH NIH HHS T32 MH078788
6 · The paper itself

Abstract

backgroundOver the past several years there has been considerable interest in the relation between emotion dysregulation and non-suicidal self-injury (NSSI), particularly given that rates of NSSI have been increasing and NSSI is a critical risk factor for suicidal behavior. To date, however, no synthesis of empirical findings exists.

methodsThe present study presents a comprehensive meta-analytic review of the literature on the association between NSSI and emotion dysregulation. A total of 48 publications, including 49 independent samples, were included in this analysis.

resultsOverall, a significant association was found between emotion dysregulation and NSSI (pooled OR = 3.03 [95% CI = 2.56-3.59]). This association was reduced but remained significant (OR = 2.40 [95% CI = 2.01-2.86]) after adjustment for publication bias. Emotion dysregulation subscales most strongly associated with NSSI included limited access to regulation strategies, non-acceptance of emotional responses, impulse control difficulties, and difficulties engaging goal-directed behavior. Lack of emotional awareness/clarity and cognitive aspects of dysregulation yielded weaker, yet significant, positive associations with NSSI.

conclusionsFindings support the notion that greater emotion dysregulation is associated with higher risk for NSSI among individuals across settings, regardless of age or sex. Furthermore, findings reveal facets of dysregulation that may have unique implications for NSSI. This meta-analysis highlights the importance of better understanding emotion dysregulation as a treatment target for preventing NSSI.

Indexed as

Self-ControlAffective SymptomsEmotionsFemaleHumansMaleRisk FactorsSelf-Injurious BehaviorSuicidal IdeationMiscellaneousSuicide

Identifiers

PMID30986729
PMCPMC6538442

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.