Evidence map›Paper›PMID 30986229›Full record

Trial reportPloS one2019

The natural history of incidental retroperitoneal schwannomas.

Akira Ogose, Hiroyuki Kawashima, Hiroshi Hatano, Takashi Ariizumi, Taro Sasaki, Tetsuro Yamagishi, Naoki Oike, Syoichi Inagawa, Naoto Endo

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Incidental detection of adrenal schwannoma: a case report.Journal of medical case reports · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. [ Giant asymptomatic anterolateral diaphragmatic hernia in an adult: report of a rare case]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025
    Article
  7. Article
  8. [Retroperitoneal schwannoma mimicking colorectal cancer metastases: a false positive result report.]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Two giant connected retroperitoneal schwannomas: a rare case report.The Journal of international medical research · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Akira OgoseDepartment of Orthopedic Surgery, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minami-Uonuma, Niigata, Japan.ORCID 0000-0001-6204-0110
Hiroyuki KawashimaDivision of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata City, Niigata, Japan.
Hiroshi HatanoDepartment of Orthopedic Surgery, Niigata Cancer Center Hospital, Kawagishicho, Chuo-ku, Niigata City, Niigata, Japan.
Takashi AriizumiDivision of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata City, Niigata, Japan.
Taro SasakiDepartment of Orthopedic Surgery, Niigata Cancer Center Hospital, Kawagishicho, Chuo-ku, Niigata City, Niigata, Japan.
Tetsuro YamagishiDivision of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata City, Niigata, Japan.
Naoki OikeDivision of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata City, Niigata, Japan.
Syoichi InagawaDivision of Radiology, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan.
Naoto EndoDivision of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata City, Niigata, Japan.
Niigata University · JPNiigata Cancer Center Hospital · JPNiigata University Medical and Dental Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural history of asymptomatic retroperitoneal schwannomas is poorly understood. This study aimed at investigating the natural history of incidental retroperitoneal schwannomas. The medical charts and imaging studies of 22 asymptomatic patients under observation for at least 12 months for retroperitoneal schwannomas were reviewed. The duration of follow-up ranged between 13 and 176 months (mean 48 months). In the 22 patients managed by the "wait and see" approach, the average tumor size at initial presentation was 51 mm, which increased to 57 mm at final follow-up. During the final follow-up, 2 patients required surgical treatment for tumor enlargement, while the remaining patients remained asymptomatic without surgery. The average growth rate of the tumors was 1.9 mm/year (range: -1.9 to 8.7 mm/year). The majority of asymptomatic retroperitoneal schwannomas demonstrate minimal growth and may be suitable for management with the "wait and see" approach.

Indexed as

NeurilemmomaRetroperitoneal NeoplasmsAdultAgedBiopsy, NeedleFemaleFollow-Up StudiesHumansMaleMiddle AgedTomography, X-Ray Computed

Identifiers

PMID30986229
PMCPMC6464223
OpenAlexW2938772014

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.