Evidence map›Paper›PMID 30985643›Full record

ArticleMedicine2019

Increasing negative lymph node count is independently associated with improved long-term survival in resectable perihilar cholangiocarcinomas.

Yunfeng Gao, Dong Xu, Yu-Shen Wu, Duke Chen, Wanchun Xiong

Abstract read
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunfeng GaoDepartment of Gynecology, Chengdu Second People's Hospital, Chengdu, Sichuan.
Dong XuDepartment of Vascular Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang.
Yu-Shen WuChongqing Key Laboratory of Molecular Oncology and Epigenetics.
Duke ChenDepartment of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wanchun XiongDepartment of Gynecology, Chengdu Second People's Hospital, Chengdu, Sichuan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the prognostic value of numbers of negative lymph nodes (NLNs) for patients with perihilar cholangiocarcinomas.The surveillance, epidemiology, and end results database was used to screen for patients with perihilar cholangiocarcinomas. Kaplan-Meier and Cox regression analyses were used for statistical evaluations. Subsequently, propensity score matching (PSM) was performed to confirm the results.A total of 938 patients with perihilar cholangiocarcinomas met the inclusion criteria. The cut-off number for the grouping of patients with different numbers of NLNs was 17. Both the univariate and multivariate survival analyses demonstrated that there was a significant improvement in terms of cancer-specific survival for patients with >17 NLNs, compared with patients with ≤17 NLNs. Then, the above results were confirmed via a PSM procedure. Additionally, the independent prognostic value of NLNs was evaluated in subgroup univariate and multivariate analyses of patients with stage I or stage II tumors.The numbers of NLNs were evaluated and determined to be important independent prognostic factors for the cancer-specific survival of patients with perihilar cholangiocarcinomas.

Indexed as

AdultAgedAged, 80 and overFemaleHumansKlatskin TumorLymphatic MetastasisLymph NodesMaleMiddle AgedNeoplasm StagingPrognosisPropensity ScoreSEER ProgramSurvival AnalysisTime Factors

Identifiers

PMID30985643
PMCPMC6485858

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.