Evidence map›Paper›PMID 30985555›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2019

Differences Between Groups of Pre-exposure Prophylaxis (PrEP) Using Couples in HIV-Negative/Unknown Relationships.

Steven A John, Gabriel Robles, Tyrel J Starks, H Jonathon Rendina

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven A JohnCenter for AIDS Intervention Research, Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI.
Gabriel RoblesCenter for HIV/AIDS Educational Studies and Training, Hunter College of the City University of New York (CUNY), New York, NY.
Tyrel J StarksCenter for HIV/AIDS Educational Studies and Training, Hunter College of the City University of New York (CUNY), New York, NY.
H Jonathon RendinaCenter for HIV/AIDS Educational Studies and Training, Hunter College of the City University of New York (CUNY), New York, NY.

Funding

QUANTITATIVE COREP30MH052776 · NIMH · MEDICAL COLLEGE OF WISCONSIN · PI PINKERTON, STEVEN · 1994 to 2018
$33.2M
Intervention to reduce drug use and HIV incidence among high PrEP priority partnered YMSMR01DA045613 · NIDA · HUNTER COLLEGE · PI STARKS, TYREL J · 2017 to 2021
$4.9M
Training Program in HIV Prevention Research EthicsR25DA031608 · NIDA · FORDHAM UNIVERSITY · PI FISHER, CELIA B · 2011 to 2025
$4.9M
Adaptation and testing of a primary care HCV group medical treatment interventionK23DA039060 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI NORTON, BRIANNA · 2015 to 2019
$948k
Developing a mobile emotion regulation intervention for HIV-positive menK01DA039030 · NIDA · HUNTER COLLEGE · PI RENDINA, H. JONATHON · 2015 to 2018
$743k
NIDA NIH HHS K01 DA039030NIDA NIH HHS K23 DA039060NIDA NIH HHS R01 DA045613NIDA NIH HHS R25 DA031608NIMH NIH HHS P30 MH052776
6 · The paper itself

Abstract

backgroundEpidemiology research is limited on the characteristics of HIV pre-exposure prophylaxis (PrEP) using couples.

settingUS nationwide sample recruited online in 2017.

methodsHIV negative/unknown gay, bisexual, and other men who have sex with men with HIV negative/unknown partners (n = 3140) were asked about individual and main partner PrEP uptake. Men were coded into the following 5 groups: (1) neither participant nor partner on PrEP, (2) partner only on PrEP, (3) participant only on PrEP, (4) both on PrEP, and (5) unknown partner PrEP use. We examined associations of demographics, relationship factors, condomless anal sex (CAS) with main and causal partners, bacterial sexually transmitted infection diagnoses, and sexual positioning with reported dyadic PrEP use using fully adjusted multinomial logistic regressions.

resultsPrEP use was 3.2% for the partner only, 5.7% for the participant only, and 4.9% for both the participant and partner; 5.6% reported not knowing their partner's PrEP use status. Men who reported any CAS with their main partner or any CAS with male casual partners were both more likely to be classified in the dyadic PrEP use group compared with the neither on PrEP group. Compared with monogamous, men in open arrangements were more likely to be classified in each of the 3 PrEP groups compared with the neither on PrEP group. Six-month bacterial sexually transmitted infection prevalence was 2.8%, 8.1%, 8.3%, 15.6%, and 4.0% for the 5 groups, respectively.

conclusionsPrEP use occurred during times of higher risk behavior engagement, but further efforts are needed to expand PrEP use to more partnered gay, bisexual, and other men who have sex with men.

Indexed as

BisexualityFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHomosexuality, MaleHumansMalePatient Acceptance of Health CarePre-Exposure ProphylaxisPrevalenceRisk-TakingSafe SexSexual and Gender MinoritiesSexual BehaviorSexually Transmitted DiseasesSexual Partners

Identifiers

PMID30985555
PMCPMC6594889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.