Evidence map›Paper›PMID 30985513›Full record

ArticleThe Pediatric infectious disease journal2019

Outcomes of a Comprehensive Retention Strategy for Youth With HIV After Transfer to Adult Care in the United States.

David Griffith, Lillian Jin, Jocelyn Childs, Roberto Posada, Jennifer Jao, Allison Agwu

Abstract read
In one paragraph

Article in The Pediatric infectious disease journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Healthcare Transition From Pediatric to Adult Care Among Youth Living With HIV in South Carolina: Retrospective Study From 2005 to 2021.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026
    Article
  4. "AIDS care · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Human Immunodeficiency Virus (HIV) Care Continuum Outcomes After Transition to Adult Care Among a Prospective Cohort of Youth With HIV in Atlanta, Georgia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Observational
  11. Factors and Outcomes Associated With Viral Suppression Trajectory Group Membership Among Youth Transitioning From Pediatric to Adult HIV Care.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Article
  12. Article
  13. Article
  14. Healthcare Transition Outcomes Among Young Adults With Perinatally Acquired Human Immunodeficiency Virus Infection in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David GriffithFrom the Departments of Pediatrics.
Lillian JinDepartments of Medical Education.
Jocelyn ChildsPediatrics.
Roberto PosadaPediatrics.
Jennifer JaoMedicine.
Allison AgwuFrom the Departments of Pediatrics.

Funding

Research Training in Pediatric Infectious DiseasesT32AI052071 · NIAID · JOHNS HOPKINS UNIVERSITY · PI AARON M MILSTONE · 2002 to 2026
$5.2M
Metabolic Effects of In Utero Antiretrovirals on HIV Exposed Uninfected InfantsK23HD070760 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI JAO, JENNIFER · 2012 to 2016
$647k
NIAID NIH HHS T32 AI052071NICHD NIH HHS K23 HD070760
6 · The paper itself

Abstract

backgroundThe retention of youth living with HIV (YLHIV) in adult care after transfer from pediatric care in the United States is a challenge. A targeted comprehensive retention strategy (CRS) may improve retention among YLHIV.

methodsA retrospective cohort study of YLHIV after transfer from pediatric to adult care for patients with at least 1 adult visit at 2 urban HIV care programs in the United States employing CRSs with internal medicine/pediatrics-trained providers, peer navigators, social workers and mental health resources. Primary outcomes were successful retention in care after transfer (≥2 provider visits in the adult clinic ≥90 days apart within 1 year of transfer) and successful transition (successful retention plus a stable HIV viral load (VL) defined as VL 1 year after transfer that was less than or equal to the VL obtained at or immediately before transfer). Logistic regression assessed factors associated with successful transition. A subgroup analysis was performed to examine rates of successful transfer and linkage from pediatric to adult clinics (attending at least 1 adult visit after transition).

resultsOf the 89 patients included in the study, 79 (89%) patients had successful retention and 53 (60%) had successful transition to the adult program. Factors associated with successful transition included non-African American race [adjusted odds ratio (aOR) = 11.26, 95% confidence interval (CI): 1.32-95.51], perinatal HIV (aOR = 8.00, 95% CI: 1.39-46.02) and CD4 count > 500 cells/mm (aOR = 5.22, 95% CI: 1.54-17.70). Of those who were retained, 53/79 (67%) had stable or improved virologic control at 1 year after transition. In a subgroup analysis, 54/56 (96%) patients who were targeted to transition successfully linked to adult care.

conclusionsOverall, YLHIV in the United States engaged in a CRS program appear to have high retention rates but suboptimal virologic control after transfer from pediatric HIV care.

Indexed as

AdolescentAdultDrug MonitoringFemaleHIV InfectionsHumansMaleRetention in CareRetrospective StudiesTransition to Adult CareTreatment OutcomeUnited StatesUrban PopulationViral LoadYoung Adult

Identifiers

PMID30985513
PMCPMC6752883

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.