Evidence map›Paper›PMID 30985508›Full record

ArticleThe Pediatric infectious disease journal2019

Successful Whole Genome Sequencing-guided Treatment of Mycoplasma hominis Ventriculitis in a Preterm Infant.

Felicia A Scaggs Huang, Joel Mortensen, Jesse Skoch, Heidi Andersen, Mary Allen Staat, Joshua K Schaffzin, David B Haslam

Abstract readCase Reports
In one paragraph

Article in The Pediatric infectious disease journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Therapeutic Drug Monitoring of Moxifloxacin to Guide Treatment ofThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Felicia A Scaggs HuangFrom the Department of Pediatrics, Division of Pediatric Infectious Diseases.
Joel MortensenDepartment of Pathology and Laboratory Medicine.
Jesse SkochDepartment of Pediatrics, Division of Neurosurgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Heidi AndersenFrom the Department of Pediatrics, Division of Pediatric Infectious Diseases.
Mary Allen StaatFrom the Department of Pediatrics, Division of Pediatric Infectious Diseases.
Joshua K SchaffzinFrom the Department of Pediatrics, Division of Pediatric Infectious Diseases.
David B HaslamFrom the Department of Pediatrics, Division of Pediatric Infectious Diseases.

Funding

Molecular Epidemiology in Children's Environmental Health Training Program (MECEH)T32ES010957 · NIEHS · UNIVERSITY OF CINCINNATI · PI Kelly J Brunst · 2001 to 2026
$11.1M
NIEHS NIH HHS T32 ES010957
6 · The paper itself

Abstract

We report a case of Mycoplasma hominis ventriculitis in a preterm neonate that was successfully identified with 16S ribosomal RNA sequencing and whole genome sequencing after failure to detect the pathogen with conventional diagnostic methods. The infant required doxycycline with subsequent clearance of the infection and no evidence of drug toxicity.

Indexed as

AdultAnti-Bacterial AgentsCerebral VentriculitisCluster AnalysisDNA, BacterialDNA, RibosomalDoxycyclineFemaleHumansInfant, NewbornInfant, PrematureMaleMycoplasma hominisMycoplasma InfectionsPhylogenyRNA, Ribosomal, 16SAnti-Bacterial AgentsDNA, BacterialDNA, RibosomalDoxycyclineRNA, Ribosomal, 16S

Identifiers

PMID30985508
PMCPMC6565488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.