ArticleInfectious diseases (London, England)2019
Biofilm formation by Staphylococcus aureus clinical isolates correlates with the infection type.
Article in Infectious diseases (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
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- The Effect of Sub-Minimal Inhibitory Concentrations of Daptomycin and Linezolid on Biofilm Formation of Methicillin ResistantTurkish journal of pharmaceutical sciences · 2025Article
- Bacterial and host interactions inFrontiers in microbiology · 2025Review
- Potential Anti-Infectious Activity of Essential Oil Chemotypes ofPlants (Basel, Switzerland) · 2024Article
- Evolutionary dynamics of the accessory genomes ofmSphere · 2024Article
- TheMicroorganisms · 2024Article
- Exploration ofFrontiers in cellular and infection microbiology · 2024Article
- The phenotypes and genotypes associated with biofilm formation among methicillin-susceptible Staphylococcus aureus (MSSA) isolates collected from a tertiary hospital in Terengganu, Malaysia.International microbiology : the official journal of the Spanish Society for Microbiology · 2023Article
- Diflunisal and Analogue Pharmacophores Mediating Suppression of Virulence Phenotypes inAntibiotics (Basel, Switzerland) · 2023Article
- Genomic epidemiology and characterization ofFrontiers in microbiology · 2023Article
- StaphylococcalInternational journal of molecular sciences · 2022Article
- Biofilm Formation ofAntibiotics (Basel, Switzerland) · 2022Article
- Determination of the ability of matrix-assisted laser desorption ionization time-of-flight mass spectrometry to identify high-biofilm-producing strains.Frontiers in microbiology · 2022Article
- Synovial Fluid-Induced Aggregation Occurs across Staphylococcus aureus Clinical Isolates and is Mechanistically Independent of Attached Biofilm Formation.Microbiology spectrum · 2021Article
- Investigation of biofilm formation in methicillin-resistant Staphylococcus aureus associated with bacteraemia in a tertiary hospital.Folia microbiologica · 2021Article
- Biofilm properties in relation to treatment outcome in patients with first-time periprosthetic hip or knee joint infection.Journal of orthopaedic translation · 2021Article
- Biofilm Formation of Multidrug-Resistant MRSA Strains Isolated from Different Types of Human Infections.Pathogens (Basel, Switzerland) · 2021Article
- Correlations of Host and Bacterial Characteristics with Clinical Parameters and Survival inJournal of clinical medicine · 2021Article
- Quorum Sensing and Toxin Production inToxins · 2020Review
- Article
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5 authors.
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Abstract
backgroundBiofilms are involved in many Staphylococcus aureus infections, but relation of biofilm formation and the infection types or the clinical outcomes remain unclear.
methodsWe measured biofilm formation, with a microtiter plate assay, of a collection of methicillin-sensitive clinical isolates from 159 invasive S. aureus infections, encompassing all cases occurring within a hospital catchment area during two years, and from additional 49 non-invasive skin infections from the same region. Results were related to available clinical and microbiological documentation.
resultsIsolates from medical device infections (intravenous line-associated and prosthetic joint infections), as well as isolates from superficial skin infections, were particularly proficient in forming biofilms. No increased biofilm-forming capacity was seen in isolates from endocarditis, osteomyelitis, or other infections. There was also a correlation of biofilm formation with the agr type of the isolates. Thicker biofilms were more resistant to antibiotic treatment in vitro. No correlation between biofilm formation and clinical outcomes was noted.
conclusionsS. aureus isolates from 'classical' biofilm-related infections, but also from superficial skin infections, are especially proficient in forming biofilms. There is, however, no obvious relation of biofilm-forming capacity of isolates and the clinical outcome of the infection, and more studies on this issue are needed.
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