Evidence map›Paper›PMID 30985222›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Familial Pulmonary Fibrosis and Hermansky-Pudlak Syndrome Rare Missense Mutations in Context.

Robert S Stearman, Amber R Cornelius, Lisa R Young, David S Conklin, Elizabeth A Mickler, Xiao Lu, Naoko Hara, Lynsey M Fettig, Tzu L Phang, Mark W Geraci

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Insights into the Pathogenesis of Pulmonary Fibrosis from Genetic Diseases.American journal of respiratory cell and molecular biology · 2022
    Review
  2. Update in Interstitial Lung Disease 2019.American journal of respiratory and critical care medicine · 2020
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Robert S Stearman1 Indiana University School of Medicine Indianapolis, Indiana.ORCID 0000-0002-7628-7066
Amber R Cornelius2 New York University School of Medicine New York, New York.
Lisa R Young3 Vanderbilt University Medical Center Nashville, Tennessee.
David S Conklin3 Vanderbilt University Medical Center Nashville, Tennessee.
Elizabeth A Mickler1 Indiana University School of Medicine Indianapolis, Indiana.
Xiao Lu4 St. John Medical Center Westlake, Ohio and.
Naoko Hara5 University of Colorado School of Medicine Aurora, Colorado.
Lynsey M Fettig5 University of Colorado School of Medicine Aurora, Colorado.
Tzu L Phang5 University of Colorado School of Medicine Aurora, Colorado.
Mark W Geraci1 Indiana University School of Medicine Indianapolis, Indiana.ORCID 0000-0002-2280-3424

Funding

RLDC: Molecular Pathway-Driven Diagnostics & Therapeutics for Rare Lung DiseasesU54HL127672 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI TRAPNELL, BRUCE C · 2014 to 2018
$3.7M
Mechanisms of Pulmonary Fibrosis in Hermansky-Pudlak SyndromeR01HL119503 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI YOUNG, LISA R. · 2013 to 2021
$3.6M
Midcareer Investigator Award in Patient-Oriented Research in Pediatric Rare Lung DiseasesK24HL143281 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI YOUNG, LISA R. · 2018 to 2022
$540k
NHLBI NIH HHS K24 HL143281NHLBI NIH HHS R01 HL119503NHLBI NIH HHS U54 HL127672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Frameshift MutationGuanine Nucleotide Exchange FactorsHaplotypesHermanski-Pudlak SyndromeHumansMembrane ProteinsMutation, MissensePulmonary FibrosisGuanine Nucleotide Exchange FactorsHPS1 protein, humanHPS4 protein, humanMembrane Proteins

Identifiers

PMID30985222
PMCPMC6835081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.