Evidence map›Paper›PMID 30984820›Full record

ArticleACS biomaterials science & engineering2019

3D Hydrogels Containing Interconnected Microchannels of Subcellular Size for Capturing Human Pathogenic

Sören B Gutekunst, Katharina Siemsen, Steven Huth, Anneke Möhring, Britta Hesseler, Michael Timmermann, Ingo Paulowicz, Yogendra Kumar Mishra, Leonard Siebert, Rainer Adelung and 1 more

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sören B GutekunstInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Katharina SiemsenInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Steven HuthInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Anneke MöhringInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Britta HesselerInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Michael TimmermannInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Ingo PaulowiczPhi-Stone AG, Kiel D-24143, Germany.
Yogendra Kumar MishraInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Leonard SiebertInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Rainer AdelungInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.
Christine Selhuber-UnkelInstitute for Materials Science, Biocompatible Nanomaterials, and Institute for Materials Science, Functional Nanomaterials, University of Kiel, Kiel D-24143, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porous hydrogel scaffolds are ideal candidates for mimicking cellular microenvironments, regarding both structural and mechanical aspects. We present a novel strategy to use uniquely designed ceramic networks as templates for generating hydrogels with a network of interconnected pores in the form of microchannels. The advantages of this new approach are the high and guaranteed interconnectivity of the microchannels, as well as the possibility to produce channels with diameters smaller than 7 μm. Neither of these assets can be ensured with other established techniques. Experiments using the polyacrylamide substrates produced with our approach have shown that the migration of human pathogenic

Identifiers

PMID30984820
PMCPMC6457568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.