Evidence map›Paper›PMID 30984790›Full record

ArticleJournal of immunology research2019

Interaction between IL-33 Gene Polymorphisms and Current Smoking with Susceptibility to Systemic Lupus Erythematosus.

Xiaohua Zhu, Lin Xie, Haihong Qin, Jun Liang, Yongsheng Yang, Jinhua Xu, Tiejun Zhang

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. IL-33/IL-31 Axis in Immune-Mediated and Allergic Diseases.International journal of molecular sciences · 2019
    Pooled it
  2. Article
  3. Review
  4. Review
  5. A broad look into the future of systemic sclerosis.Therapeutic advances in musculoskeletal disease · 2022
    Review
  6. Mechanisms of Environment-Induced Autoimmunity.Annual review of pharmacology and toxicology · 2021
    Article
  7. IL-33 in Rheumatic Diseases.Frontiers in medicine · 2021
    Review
  8. Article
  9. BioMed research international · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaohua ZhuDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Lin XieDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.ORCID 0000-0002-8850-6764
Haihong QinDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.ORCID 0000-0002-0253-1433
Jun LiangDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yongsheng YangDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Jinhua XuDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.ORCID 0000-0001-8580-9164
Tiejun ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai 200040, China.ORCID 0000-0002-5187-7393
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study is aimed at exploring the relation between IL-33 single-nucleotide polymorphisms (SNPs) and the risk of systemic lupus erythematosus (SLE).

methodsSNPStats (online software) was used to test the Hardy-Weinberg equilibrium in controls. Generalized multifactor dimensionality reduction (GMDR) was adopted to screen the preferable interaction between IL-33 SNPs and current smoking.

resultsLogistic regression analysis based on the fundamental data of age, gender, BMI, current smoking, and alcohol drinking showed that both

conclusionsThe

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAdultAlcohol DrinkingAllelesAsian PeopleFemaleGene FrequencyGenetic Association StudiesGenotypeHaplotypesHumansInterleukin-33Lupus Erythematosus, SystemicMaleMiddle AgedIL33 protein, humanInterleukin-33

Identifiers

PMID30984790
PMCPMC6432724
OpenAlexW2921411177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.