Evidence map›Paper›PMID 30984759›Full record

ArticleFrontiers in medicine2019

Direct-to-Consumer Genetic Testing's Red Herring: "Genetic Ancestry" and Personalized Medicine.

Mwenza Blell, M A Hunter

Abstract read
In one paragraph

Article in Frontiers in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Impacts of personal DNA ancestry testing.Journal of community genetics · 2021
    Article
  6. In Defense of Direct-to-Consumer Genetic Testing.Integrative medicine (Encinitas, Calif.) · 2019
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mwenza BlellPolicy, Ethics and Life Sciences Research Centre, School of Geography, Politics and Sociology, Newcastle University, Newcastle-upon-Tyne, United Kingdom.
M A HunterDepartment of Philosophy, Logic, and Scientific Method, Centre for Philosophy of Natural and Social Science (CPNSS), The London School of Economics and Political Science, London, United Kingdom.

Funding

Wellcome Trust 209829/Z/17/Z
6 · The paper itself

Abstract

The growth in the direct-to-consumer genetic testing industry poses a number of challenges for healthcare practice, among a number of other areas of concern. Several companies providing this service send their customers reports including information variously referred to as genetic ethnicity, genetic heritage, biogeographic ancestry, and genetic ancestry. In this article, we argue that such information should not be used in healthcare consultations or to assess health risks. Far from representing a move toward personalized medicine, use of this information poses risks both to patients as individuals and to racialized ethnic groups because of the way it misrepresents human genetic diversity.

Indexed as

ethicsethnicitygenetic testingpersonalized medicinerace

Identifiers

PMID30984759
PMCPMC6449432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.