Evidence map›Paper›PMID 30984614›Full record

ArticleFrontiers in oncology2019

Prolonged Response Induced by Single Agent Vemurafenib in a

Louis Garnier, François Ducray, Clotilde Verlut, Marcella-Ionela Mihai, Françoise Cattin, Antoine Petit, Elsa Curtit

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Targeted Therapy for BRAF Mutant Brain Tumors.Current treatment options in oncology · 2021
    Review
  8. Article
  9. Treatment ofSurgical neurology international · 2021
    Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Louis GarnierDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
François DucrayDepartment of Neuro-Oncology, Hospices Civils de Lyon, Lyon, France.
Clotilde VerlutDepartment of Neurology, University Hospital of Besançon, Besançon, France.
Marcella-Ionela MihaiDepartment of Pathology, University Hospital of Besançon, Besançon, France.
Françoise CattinDepartment of Radiology, University Hospital of Besançon, Besançon, France.
Antoine PetitDepartment of Neurosurgery, University Hospital of Besançon, Besançon, France.
Elsa CurtitDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Centre Hospitalier Universitaire de Besançon · FRHospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal ganglioglioma is a rare low-grade, slow-growing tumor of the central nervous system affecting mostly children and young adults. After surgery, some patients show tumor recurrence and/or malignant transformation. Gangliogliomas harbor molecular deficiencies such as mutations in the B-rapidly accelerated fibrosarcoma (

Indexed as

BRAFcentral nervous system tumorgangliogliomasafetyspinal cordtumor regressionvemurafenib

Identifiers

PMID30984614
PMCPMC6448025
OpenAlexW2919430852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.