Evidence map›Paper›PMID 30984487›Full record

ArticleChemistryOpen2019

Self-Assembly of Copper Polypyridyl Supramolecular Metallopolymers to Achieve Enhanced Anticancer Efficacy.

Lanhai Lai, Dong Luo, Ting Liu, Wenjie Zheng, Tianfeng Chen, Dan Li

Abstract read
In one paragraph

Article in ChemistryOpen, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Metal-Coordinated Supramolecular Self-Assemblies for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lanhai LaiDepartment of Chemistry Jinan University Guangzhou 510632 GuangDong Province China) .
Dong LuoDepartment of Chemistry Jinan University Guangzhou 510632 GuangDong Province China) .
Ting LiuDepartment of Chemistry Jinan University Guangzhou 510632 GuangDong Province China) .
Wenjie ZhengDepartment of Chemistry Jinan University Guangzhou 510632 GuangDong Province China) .
Tianfeng ChenDepartment of Chemistry Jinan University Guangzhou 510632 GuangDong Province China) .
Dan LiDepartment of Chemistry Jinan University Guangzhou 510632 GuangDong Province China) .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-assembled functional supramolecular metallopolymers have demonstrated application potential in cancer therapy. Herein, a copper polypyridyl complex was found able to self-assemble into a supramolecular metallopolymer driven by the intermolecular interactions, which could enhance the uptake in cancer cells through endocytosis, and thus effectively inhibiting tumor growth in vivo without damaging to the major organs. This study provides a facile way to achieve enhanced anticancer efficacy by using self-assembled metallopolymers.

Indexed as

anticancer activitycopper(II) complexesmetallopolymersself-assembly

Identifiers

PMID30984487
PMCPMC6445060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.