Evidence map›Paper›PMID 30984483›Full record

ArticlePeerJ2019

Overexpression of lncRNA H19 changes basic characteristics and affects immune response of bovine mammary epithelial cells.

Xuezhong Li, Hao Wang, Yanfen Zhang, Jinjing Zhang, Shaopei Qi, Yong Zhang, Ming-Qing Gao

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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  20. Transcriptional Profiling of Exosomes Derived fromOxidative medicine and cellular longevity · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xuezhong Li *College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Hao Wang *College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Yanfen ZhangNorthwest A&F University hospital, Northwest A&F University, Yangling, China.
Jinjing ZhangCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Shaopei QiCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Yong ZhangCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Ming-Qing GaoCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Northwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function of long non-coding RNA H19 (H19) on cell proliferation has been observed in various cell types, and the increased expression of H19 was also found in the lipopolysaccharide (LPS)-induced inflammatory bovine mammary epithelial cells (MAC-T). However, the roles of H19 in the inflammatory response and physiological functions of bovine mammary epithelial cell are not clear. In the present study, we found that overexpression of H19 in MAC-T cells significantly promoted cell proliferation, increased the protein and mRNA level of β-casein, and enhanced the expression of tight junction (TJ)-related proteins while inhibited

Indexed as

Bovine mastitisEpithelial cellsImmnue responseLipopolysaccharideLong non-coding RNA H19

Identifiers

PMID30984483
PMCPMC6452850
OpenAlexW2931024069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.