Evidence map›Paper›PMID 30984433›Full record

ArticleCase reports in hematology2019

Bone Marrow Aspirate Clot: A Useful Technique in Diagnosis and Follow-Up of Hematological Disorders.

Lucas Oliveira Cantadori, Rafael Dezen Gaiolla, Ligia Niero-Melo, Cristiano Claudino Oliveira

Abstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucas Oliveira CantadoriSão Paulo State University (UNESP), Medical School of Botucatu, Department of Internal Medicine, Botucatu, SP, Brazil.ORCID 0000-0003-0436-1842
Rafael Dezen GaiollaSão Paulo State University (UNESP), Medical School of Botucatu, Department of Internal Medicine, Botucatu, SP, Brazil.
Ligia Niero-MeloSão Paulo State University (UNESP), Medical School of Botucatu, Department of Internal Medicine, Botucatu, SP, Brazil.
Cristiano Claudino OliveiraSão Paulo State University (UNESP), Medical School of Botucatu, Department of Pathology, Botucatu, SP, Brazil.ORCID 0000-0001-6682-5230

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone marrow biopsy is a diagnostic tool largely used in the evaluation of a broad number of disorders that could affect the hematopoietic system. Differently, bone marrow aspirate clot technique is rarely performed even though it has been described in literature. Here, we highlight the utility of the bone marrow aspirate clot, exemplifying through the discussion of three clinical cases in which this technique was used for diagnosis and follow-up purposes: megaloblastic hemopathy, multiple myeloma, and chronic lymphocytic leukemia. Bone marrow clot analysis increases sensitivity to diagnose hemopathies and offers the possibility of morphological evaluation and anatomopathological study, with the advantage of not needing decalcification processes, hence improving antigenic expression in immunohistochemical and FISH techniques. It is an easy-to-perform technique, offering a quick, reliable, and more comfortable procedure for patients.

Identifiers

PMID30984433
PMCPMC6431525

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.