ReviewInternational journal of hypertension2019
The Mechanism of Acupuncture in Treating Essential Hypertension: A Narrative Review.
Review in International journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Efficacy and safety of community-based moxibustion for primary hypertension: A randomized controlled trial with patient preference arms.Journal of clinical hypertension (Greenwich, Conn.) · 2023Trial
- Acupuncture Is Effective at Reducing the Risk of Stroke in Patients with Migraines: A Real-World, Large-Scale Cohort Study with 19-Years of Follow-Up.International journal of environmental research and public health · 2023Trial
- Effect of acupuncture on ischemic stroke patients with hypertension: a randomized clinical trail.Frontiers in neurologyTrial
- Basic and clinical research on acupuncture for post-stroke depression: A narrative review.World journal of methodology · 2026Review
- Effects of transcutaneous electrical acupoint stimulation on body temperature, hemodynamic responses, and recovery in patients undergoing open spinal surgery.American journal of translational research · 2026Article
- The Effect of Electroacupuncture on Microcirculation in Patients With Hypertension and Cognitive Impairment: Protocol for a Multicenter Randomized Controlled Trial.JMIR research protocols · 2025Article
- Pharmacological and toxicological effects of Jiangfangbaoxin and determination of its components in the blood of spontaneously hypertensive rats.Scientific reports · 2025Article
- Acupuncture for Essential Hypertension and Endothelial Dysfunction: A Randomized Clinical Trial.Arquivos brasileiros de cardiologia · 2025Article
- Exploring the potential effect of electroacupuncture on cardiovascular function and lipid profiles in spontaneously hypertensive rats.Integrative medicine research · 2024Article
- Integrative Analysis of Acupuncture Targets and Immune Genes in Diabetes, Diabetic Peripheral Neuropathy, and Adjunct Therapy of Cancer.Journal of multidisciplinary healthcare · 2024Article
- Acupuncture influences multiple diseases by regulating gut microbiota.Frontiers in cellular and infection microbiology · 2024Review
- Adenosine AFrontiers in cardiovascular medicine · 2023Article
- Acupuncture in Arterial Hypertension: Evaluation of its Efficacy with Both Office and Ambulatory Blood Pressure Measurements.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022Article
- Electroacupuncture Attenuated Phenotype Transformation of Vascular Smooth Muscle Cells via PI3K/Akt and MAPK Signaling Pathways in Spontaneous Hypertensive Rats.Chinese journal of integrative medicine · 2022Article
- Can Post-Exercise Hemodynamic Response Be Influenced by Different Recovery Methods in Paraplegic Sportsmen?International journal of environmental research and public health · 2022Article
- Effect of Acupuncture on Blood Pressure and Metabolic Profile Among Patients With Essential Hypertension: Protocol of a Randomized Clinical Trial.Frontiers in cardiovascular medicine · 2022Article
- Article
- Acupuncture for Treating Hypertension and Type 2 Diabetes Mellitus as Comorbidities in Patients with COVID-19.Medical acupuncture · 2021Review
- Proteomics analysis of the hypothalamus in spontaneously hypertensive rats treated with twirling reinforcing manipulation, twirling reducing manipulation or electroacupuncture.Experimental and therapeutic medicine · 2021Article
- Improvement of intestinal flora: accompany with the antihypertensive effect of electroacupuncture on stage 1 hypertension.Chinese medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Essential hypertension has a high incidence worldwide, and patients with essential hypertension endure a lifetime of medication, leading to a heavy economic burden on the patient's family and causing serious impacts on the patient's quality of life. Much evidence has demonstrated that acupuncture as an adjunctive therapy can lower blood pressure in patients with hypertension, but the mechanism of its action is unclear. This article reviews the research from 2000 to 2018 regarding the mechanism of acupuncture for hypertension, and we summarize the current knowledge about using acupuncture for hypertension. We found that the mechanism whereby acupuncture lowers blood pressure is related to the regulation of renin-angiotensin-aldosterone system, vascular endothelium, oxidative stress, neuroendocrine system, and so on. Besides, there may be cross-talk between multiple systems and multiple targets. We also investigate the influence factors of acupuncture for hypertension. These results may provide evidence and research ideas for the treatment of hypertension via acupuncture.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.