Evidence map›Paper›PMID 30984354›Full record

ArticleNutrition research and practice2019

Daily walnut intake improves metabolic syndrome status and increases circulating adiponectin levels: randomized controlled crossover trial.

Hyo-Jeong Hwang, Yanan Liu, Hyun-Sook Kim, Heeseung Lee, Yunsook Lim, Hyunjin Park

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03267901 (Effects of Daily Walnut Intake Among the Subjects With Metabolic Syndrome in South Korea), which is not on this map. Cited by 23 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 10 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03267901 nacompletednot on this map

Effects of Daily Walnut Intake Among the Subjects With Metabolic Syndrome in South Korea

TypeinterventionalSponsorICAN Nutrition Education and ResearchRan2015 to 2017Enrolled119ConditionsMetabolic SyndromeArmsfood
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 10 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Effects of Walnut (Juglans regia L.) on Blood Pressure and Endothelial Function in Adults: A Systematic Review and Dose-Response Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hyo-Jeong HwangICAN Nutrition Education and Research, 20, Gukjegeumyung-ro 7-gil, Yeongdeungpo-gu, Seoul 07340, Republic of Korea.ORCID https://orcid.org/0000-0003-2041-1934
Yanan LiuDepartment of Food and Nutrition, Sookmyung Women's University, Seoul 04310, Republic of Korea.ORCID https://orcid.org/0000-0002-6170-9414
Hyun-Sook KimDepartment of Food and Nutrition, Sookmyung Women's University, Seoul 04310, Republic of Korea.ORCID https://orcid.org/0000-0002-1095-3660
Heeseung LeeDepartment of Food and Nutrition, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID https://orcid.org/0000-0003-1238-9984
Yunsook LimDepartment of Food and Nutrition, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID https://orcid.org/0000-0002-3408-8595
Hyunjin ParkICAN Nutrition Education and Research, 20, Gukjegeumyung-ro 7-gil, Yeongdeungpo-gu, Seoul 07340, Republic of Korea.ORCID https://orcid.org/0000-0002-4869-0798
Kyung Hee University · KRSangmyung University · KRSookmyung Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesSeveral previous studies have investigated whether regular walnut consumption positively changes heart-health-related parameters. The aim of this study was to investigate the effects of daily walnut intake on metabolic syndrome (MetS) status and other metabolic parameters among subjects with MetS. SUBJECTS/

methodsThis study was a two-arm, randomized, controlled crossover study with 16 weeks of each intervention (45 g of walnuts or iso-caloric white bread) with a 6 week washout period between interventions. Korean adults with MetS (n = 119) were randomly assigned to one of two sequences; 84 subjects completed the trial. At each clinic visit (at 0, 16, 22, and 38 weeks), MetS components, metabolic parameters including lipid profile, hemoglobin A1c (HbA1c), adiponectin, leptin, and apolipoprotein B, as well as anthropometric and bioimpedance data were obtained.

resultsDaily walnut consumption for 16 weeks improved MetS status, resulting in 28.6%-52.8% reversion rates for individual MetS components and 51.2% of participants with MetS at baseline reverted to a normal status after the walnut intervention. Significant improvements after walnut intake, compared to control intervention, in high-density lipoprotein cholesterol (HDL-C) (

conclusionA dietary supplement of 45 g of walnuts for 16 weeks favorably changed MetS status by increasing the concentration of HDL-C and decreasing fasting glucose level. Furthermore, consuming walnuts on a daily basis changed HbA1c and circulating adiponectin levels among the subjects with MetS. This trial is registered at ClinicalTrials.gov as NCT03267901.

Indexed as

adiponectincross-over studiesjuglansMetabolic syndrome

Identifiers

PMID30984354
PMCPMC6449547
OpenAlexW2930852664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.