Evidence map›Paper›PMID 30984348›Full record

ArticleWorld journal of gastrointestinal oncology2019

Impact of time from diagnosis to chemotherapy in advanced gastric cancer: A Propensity Score Matching Study to Balance Prognostic Factors.

Tsutomu Nishida, Aya Sugimoto, Ryo Tomita, Yu Higaki, Naoto Osugi, Kei Takahashi, Kaori Mukai, Tokuhiro Matsubara, Dai Nakamatsu, Shiro Hayashi and 4 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Tsutomu NishidaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan. tnishida.gastro@gmail.com.
Aya SugimotoDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Ryo TomitaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Yu HigakiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Naoto OsugiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Kei TakahashiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Kaori MukaiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Tokuhiro MatsubaraDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Dai NakamatsuDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Shiro HayashiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Masashi YamamotoDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Sachiko NakajimaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Koji FukuiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Masami InadaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 560-8565, Japan.
Toyonaka Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is unclear whether treatment delay affects the clinical outcomes of chemotherapy in advanced gastric cancer (A-GC).

aimTo assess whether treatment delay affects the clinical outcomes of chemotherapy in A-GC.

methodsThis single-center retrospective study examined consecutive patients with A-GC between April 2012 and July 2018. In total, 110 patients with stage IV A-GC who underwent chemotherapy were enrolled. We defined the wait time (WT) as the interval between diagnosis and chemotherapy initiation. We evaluated the influence of WT on overall survival (OS).

resultsThe mean OS was 303 d. The median WT was 17 d. We divided the patients into early and elective WT groups, with a 2-wk cutoff point. There were 46 and 64 patients in the early and elective WT groups, respectively. Compared with the elective WT group, the early WT group had significantly lower albumin (Alb) levels and higher neutrophil/lymphocyte ratios and C-reactive protein (CRP) levels but not a lower performance status. The elective WT group underwent more combination chemotherapy than did the early WT group. OS was different between the two groups (230 d

conclusionA longer WT in patients with A-GC does not appear to be associated with a worse prognosis.

Indexed as

Advanced gastric cancerChemotherapyOverall survivalPrognosisWaiting time

Identifiers

PMID30984348
PMCPMC6451925
OpenAlexW2909570218

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.