Evidence map›Paper›PMID 30984332›Full record

ArticleOxidative medicine and cellular longevity2019

1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation.

Yihang Yang, Bo Pang, Zihao Liu, Jie Li, Zhen Zhang, Rui Zhang, Xianzeng Hou, Hua Guo, Lingyi Chi, Qi Pang and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Neurotoxicity and Underlying Mechanisms of Endogenous Neurotoxins.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yihang YangDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.ORCID 0000-0003-1534-1986
Bo PangDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.ORCID 0000-0002-9176-9282
Zihao LiuMedical College of Nanchang University, Nanchang, Jiangxi 330000, China.
Jie LiDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
Zhen ZhangDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
Rui ZhangDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
Xianzeng HouDepartment of Neurosurgery, Qianfoshan Hospital affiliated to Shandong University, Shandong 250014, China.
Hua GuoDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
Lingyi ChiDepartment of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute of Shandong University, Jinan, 250012 Shandong, China.
Qi PangDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
Tao XinDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.ORCID 0000-0002-8797-3002
Shandong University · CNNanchang University · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several

Indexed as

AnimalsApoptosisCarbolinesDisease Models, AnimalDopaminergic NeuronsInflammationMaleOxidative StressRatsRats, Wistar1-trichloromethyl-1,2,3,4-tetrahydro-beta-carbolineCarbolines

Identifiers

PMID30984332
PMCPMC6431519
OpenAlexW2921543498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.